Literature DB >> 29896700

Histological Observation of Teratogenic Phenotypes Induced in Frog Embryo Assays.

Mark E Pownall1, Margaret S Saha2.   

Abstract

Amphibian embryos have long served as an ideal model for teratogenicity testing. While whole-mount embryo observations can be utilized, histological observation of teratogenic phenotypes provides a wealth of additional information that can lead to mechanistic insights. In this chapter, detailed protocols for two methods of sectioning embryos as well as a guide for histological analysis is provided.

Entities:  

Keywords:  Cryosectioning; Embryo; FETAX; Histology; Paraffin sectioning; Sectioning; Teratogen; Toxicology; Xenopus

Mesh：

Substances：

Year:  2018        PMID： 29896700      PMCID： PMC6813839          DOI： 10.1007/978-1-4939-7883-0_16

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  11 in total

1.  Enhancing the predictive validity of Frog Embryo Teratogenesis Assay--Xenopus (FETAX).

Authors:  Douglas J Fort; Robbin R Paul
Journal:  J Appl Toxicol       Date:  2002 May-Jun       Impact factor: 3.446

2.  Multichannel wholemount fluorescent and fluorescent/chromogenic in situ hybridization in Xenopus embryos.

Authors:  Peter D Vize; Kyle E McCoy; Xiaolan Zhou
Journal:  Nat Protoc       Date:  2009       Impact factor: 13.491

Review 3.  The ImageJ ecosystem: An open platform for biomedical image analysis.

Authors:  Johannes Schindelin; Curtis T Rueden; Mark C Hiner; Kevin W Eliceiri
Journal:  Mol Reprod Dev       Date:  2015-07-07       Impact factor: 2.609

4.  Whole-mount fluorescence immunocytochemistry on Xenopus embryos.

Authors:  Chanjae Lee; Esther Kieserman; Ryan S Gray; Tae Joo Park; John Wallingford
Journal:  CSH Protoc       Date:  2008-02-01

Review 5.  DAPI: a DNA-specific fluorescent probe.

Authors:  J Kapuscinski
Journal:  Biotech Histochem       Date:  1995-09       Impact factor: 1.718

6.  Hematoxylin and eosin staining of tissue and cell sections.

Authors:  Andrew H Fischer; Kenneth A Jacobson; Jack Rose; Rolf Zeller
Journal:  CSH Protoc       Date:  2008-05-01

7.  Characterization of tweety gene (ttyh1-3) expression in Xenopus laevis during embryonic development.

Authors:  Andrew D Halleran; Morgan Sehdev; Brian A Rabe; Ryan W Huyck; Cheyenne C Williams; Margaret S Saha
Journal:  Gene Expr Patterns       Date:  2014-12-23       Impact factor: 1.224

8.  Comparative teratogenicity of chlorpyrifos and malathion on Xenopus laevis development.

Authors:  Patrizia Bonfanti; Anita Colombo; Federica Orsi; Ilaria Nizzetto; Manuela Andrioletti; Renato Bacchetta; Paride Mantecca; Umberto Fascio; Giovanni Vailati; Claudio Vismara
Journal:  Aquat Toxicol       Date:  2004-12-10       Impact factor: 4.964

9.  An evaluation of confocal versus conventional imaging of biological structures by fluorescence light microscopy.

Authors:  J G White; W B Amos; M Fordham
Journal:  J Cell Biol       Date:  1987-07       Impact factor: 10.539

10.  Xenbase, the Xenopus model organism database; new virtualized system, data types and genomes.

Authors:  J Brad Karpinka; Joshua D Fortriede; Kevin A Burns; Christina James-Zorn; Virgilio G Ponferrada; Jacqueline Lee; Kamran Karimi; Aaron M Zorn; Peter D Vize
Journal:  Nucleic Acids Res       Date:  2014-10-13       Impact factor: 16.971
View more
  2 in total

1.  Expression of trpv channels during Xenopus laevis embryogenesis.

Authors:  Chen Dong; Sudip Paudel; Nana Yaa Amoh; Margaret S Saha
Journal:  Gene Expr Patterns       Date:  2018-10-13       Impact factor: 1.224

2.  Xenopus embryos show a compensatory response following perturbation of the Notch signaling pathway.

Authors:  Grace E Solini; Mark E Pownall; Molly J Hillenbrand; Claire E Tocheny; Sudip Paudel; Andrew D Halleran; Catherine H Bianchi; Ryan W Huyck; Margaret S Saha
Journal:  Dev Biol       Date:  2019-12-30       Impact factor: 3.582
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.