Literature DB >> 29895826

Immunological mechanisms of human resistance to persistent Mycobacterium tuberculosis infection.

Jason D Simmons1, Catherine M Stein2,3, Chetan Seshadri4, Monica Campo4, Galit Alter5, Sarah Fortune6, Erwin Schurr7, Robert S Wallis3,8, Gavin Churchyard8, Harriet Mayanja-Kizza9, W Henry Boom3, Thomas R Hawn4.   

Abstract

Mycobacterium tuberculosis is a leading cause of mortality worldwide and establishes a long-lived latent infection in a substantial proportion of the human population. Multiple lines of evidence suggest that some individuals are resistant to latent M. tuberculosis infection despite long-term and intense exposure, and we term these individuals 'resisters'. In this Review, we discuss the epidemiological and genetic data that support the existence of resisters and propose criteria to optimally define and characterize the resister phenotype. We review recent insights into the immune mechanisms of M. tuberculosis clearance, including responses mediated by macrophages, T cells and B cells. Understanding the cellular mechanisms that underlie resistance to M. tuberculosis infection may reveal immune correlates of protection that could be utilized for improved diagnostics, vaccine development and novel host-directed therapeutic strategies.

Entities:  

Mesh：

Year:  2018        PMID： 29895826      PMCID： PMC6278832          DOI： 10.1038/s41577-018-0025-3

Source DB:  PubMed          Journal:  Nat Rev Immunol        ISSN： 1474-1733            Impact factor:   108.555


  163 in total

1.  The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy.

Authors:  Robert O Watson; Samantha L Bell; Donna A MacDuff; Jacqueline M Kimmey; Elie J Diner; Joanna Olivas; Russell E Vance; Christina L Stallings; Herbert W Virgin; Jeffery S Cox
Journal:  Cell Host Microbe       Date:  2015-06-02       Impact factor: 21.023

2.  Epidemiology of tuberculosis aboard a ship.

Authors:  M A Hardy; H H Schmidek
Journal:  JAMA       Date:  1968-01-15       Impact factor: 56.272

3.  Antigen-specific and persistent tuberculin anergy in a cohort of pulmonary tuberculosis patients from rural Cambodia.

Authors:  Julio C Delgado; Eunice Y Tsai; Sok Thim; Andres Baena; Vassiliki A Boussiotis; Jean-Marc Reynes; Sun Sath; Pierre Grosjean; Edmond J Yunis; Anne E Goldfeld
Journal:  Proc Natl Acad Sci U S A       Date:  2002-05-28       Impact factor: 11.205

4.  Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Authors:  Aravind Subramanian; Pablo Tamayo; Vamsi K Mootha; Sayan Mukherjee; Benjamin L Ebert; Michael A Gillette; Amanda Paulovich; Scott L Pomeroy; Todd R Golub; Eric S Lander; Jill P Mesirov
Journal:  Proc Natl Acad Sci U S A       Date:  2005-09-30       Impact factor: 11.205

5.  Impact of social interactions in the community on the transmission of tuberculosis in a high incidence area.

Authors:  C N Classen; R Warren; M Richardson; J H Hauman; R P Gie; J H Ellis; P D van Helden; N Beyers
Journal:  Thorax       Date:  1999-02       Impact factor: 9.139

6.  Variants in toll-like receptors 2 and 9 influence susceptibility to pulmonary tuberculosis in Caucasians, African-Americans, and West Africans.

Authors:  Digna Rosa Velez; Christian Wejse; Martin E Stryjewski; Eduardo Abbate; William F Hulme; Jamie L Myers; Rosa Estevan; Sara G Patillo; Rikke Olesen; Alessandra Tacconelli; Giorgio Sirugo; John R Gilbert; Carol D Hamilton; William K Scott
Journal:  Hum Genet       Date:  2009-09-22       Impact factor: 4.132

7.  Expression profiling of sodium butyrate (NaB)-treated cells: identification of regulation of genes related to cytokine signaling and cancer metastasis by NaB.

Authors:  Jeena Joseph; Giridhar Mudduluru; Sini Antony; Surabhi Vashistha; Parthasarathi Ajitkumar; Kumaravel Somasundaram
Journal:  Oncogene       Date:  2004-08-19       Impact factor: 9.867

8.  Attack rate of tuberculosis in a 5-year period among close family contacts of tuberculous patients under domiciliary treatment with isoniazid plus PAS or isoniazid alone.

Authors:  S Devadatta; J J Dawson; W Fox; B Janardhanam; S Radhakrishna; C V Ramakrishnan; S Velu
Journal:  Bull World Health Organ       Date:  1970       Impact factor: 9.408

9.  A mycobacterial lipoarabinomannan specific monoclonal antibody and its F(ab') fragment prolong survival of mice infected with Mycobacterium tuberculosis.

Authors:  B Hamasur; M Haile; A Pawlowski; U Schroder; G Kallenius; S B Svenson
Journal:  Clin Exp Immunol       Date:  2004-10       Impact factor: 4.330

10.  Susceptibility of mice deficient in CD1D or TAP1 to infection with Mycobacterium tuberculosis.

Authors:  S M Behar; C C Dascher; M J Grusby; C R Wang; M B Brenner
Journal:  J Exp Med       Date:  1999-06-21       Impact factor: 14.307
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  78 in total

Review 1.  Genetics and evolution of tuberculosis pathogenesis: New perspectives and approaches.

Authors:  Michael L McHenry; Scott M Williams; Catherine M Stein
Journal:  Infect Genet Evol       Date:  2020-01-22       Impact factor: 3.342

Review 2.  The Many Hosts of Mycobacteria 8 (MHM8): A conference report.

Authors:  Michelle H Larsen; Karen Lacourciere; Tina M Parker; Alison Kraigsley; Jacqueline M Achkar; Linda B Adams; Kathryn M Dupnik; Luanne Hall-Stoodley; Travis Hartman; Carly Kanipe; Sherry L Kurtz; Michele A Miller; Liliana C M Salvador; John S Spencer; Richard T Robinson
Journal:  Tuberculosis (Edinb)       Date:  2020-02-11       Impact factor: 3.131

3.  Single-Dose Mucosal Immunotherapy With Chimpanzee Adenovirus-Based Vaccine Accelerates Tuberculosis Disease Control and Limits Its Rebound After Antibiotic Cessation.

Authors:  Sam Afkhami; Rocky Lai; Michael R D'agostino; Maryam Vaseghi-Shanjani; Anna Zganiacz; Yushi Yao; Mangalakumari Jeyanathan; Zhou Xing
Journal:  J Infect Dis       Date:  2019-09-13       Impact factor: 5.226

4.  Importance of Study Design and Phenotype Definition in Ongoing Studies of Resistance to Latent Mycobacterium tuberculosis Infection.

Authors:  Catherine M Stein; Harriet Mayanja-Kizza; Thomas R Hawn; W Henry Boom
Journal:  J Infect Dis       Date:  2020-03-02       Impact factor: 5.226

5.  Capsular glycan recognition provides antibody-mediated immunity against tuberculosis.

Authors:  Tingting Chen; Caroline Blanc; Yanyan Liu; Elise Ishida; Sarah Singer; Jiayong Xu; Maju Joe; Elizabeth R Jenny-Avital; John Chan; Todd L Lowary; Jacqueline M Achkar
Journal:  J Clin Invest       Date:  2020-04-01       Impact factor: 14.808

6.  Single-Nucleotide Variants in the AIM2 - Absent in Melanoma 2 Gene (rs1103577) Associated With Protection for Tuberculosis.

Authors:  Mariana Brasil de Andrade Figueira; Dhêmerson Souza de Lima; Antonio Luiz Boechat; Milton Gomes do Nascimento Filho; Irineide Assumpção Antunes; Joycenéa da Silva Matsuda; Thaís Rodrigues de Albuquerque Ribeiro; Luana Sousa Felix; Ariane Senna Fonseca Gonçalves; Allyson Guimarães da Costa; Rajendranath Ramasawmy; Alessandra Pontillo; Mauricio Morishi Ogusku; Aya Sadahiro
Journal:  Front Immunol       Date:  2021-04-01       Impact factor: 7.561

Review 7.  The End of the Binary Era: Revisiting the Spectrum of Tuberculosis.

Authors:  Philana Ling Lin; JoAnne L Flynn
Journal:  J Immunol       Date:  2018-11-01       Impact factor: 5.422

8.  Reconsidering the Optimal Immune Response to Mycobacterium tuberculosis.

Authors:  Liku B Tezera; Salah Mansour; Paul Elkington
Journal:  Am J Respir Crit Care Med       Date:  2020-02-15       Impact factor: 21.405

Review 9.  Tuberculosis Vaccine Development: Progress in Clinical Evaluation.

Authors:  Suraj B Sable; James E Posey; Thomas J Scriba
Journal:  Clin Microbiol Rev       Date:  2019-10-30       Impact factor: 26.132

10.  Resistance to Mycobacterium tuberculosis Infection Among Household Contacts: A Multinational Study.

Authors:  Davit Baliashvili; Neel R Gandhi; Soyeon Kim; Michael Hughes; Vidya Mave; Alberto Mendoza-Ticona; Pedro Gonzales; Kim Narunsky; Poongulali Selvamuthu; Sharlaa Badal-Faesen; Caryn Upton; Linda Naini; Elizabeth Smith; Amita Gupta; Gavin Churchyard; Susan Swindells; Anneke Hesseling; N Sarita Shah
Journal:  Clin Infect Dis       Date:  2021-09-15       Impact factor: 9.079
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