| Literature DB >> 2989485 |
M T Wu, A W Douglas, D L Ondeyka, L G Payne, T J Ikeler, H Joshua, A A Patchett.
Abstract
The synthesis and some of the spectral properties of N2-[(S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline (lisinopril, MK-521) are described. This compound inhibits angiotensin-converting enzyme with an IC50 of 1.2 X 10(-9) M.Entities:
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Year: 1985 PMID： 2989485 DOI： 10.1002/jps.2600740330
Source DB: PubMed Journal: J Pharm Sci ISSN： 0022-3549 Impact factor: 3.534