Literature DB >> 29891597

Emergence of Azole-Resistant Aspergillus fumigatus from Immunocompromised Hosts in India.

Yubhisha Dabas1, Immaculata Xess2, Sameer Bakshi3, Manoranjan Mahapatra4, Rachna Seth5.   

Abstract

This prospective study shows that the rate of azole-resistant Aspergillus fumigatus (ARAF) in an immunocompromised Indian patient population with invasive aspergillosis (IA) is low, 6/706 (0.8%). This low rate supports the continued use of voriconazole as the first line of treatment. However, the ARAF isolates from India in this study exhibited three kinds of unreported cyp51A mutations, of which two were at hot spots, G54R and P216L, while one was at codon Y431C.
Copyright © 2018 American Society for Microbiology.

Entities:  

Keywords:  India; antifungal susceptibility testing; azole-resistant Aspergillus fumigatus; cyp51A mutations; immunocompromised hosts; invasive aspergillosis; risk factor

Mesh：

Substances：

Year:  2018        PMID： 29891597      PMCID： PMC6105863          DOI： 10.1128/AAC.02264-17

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  59 in total

1.  Laboratory detection and identification of Aspergillus species by microscopic observation and culture: the traditional approach.

Authors:  N McClenny
Journal:  Med Mycol       Date:  2005-05       Impact factor: 4.076

2.  Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America.

Authors:  Thomas J Walsh; Elias J Anaissie; David W Denning; Raoul Herbrecht; Dimitrios P Kontoyiannis; Kieren A Marr; Vicki A Morrison; Brahm H Segal; William J Steinbach; David A Stevens; Jo-Anne van Burik; John R Wingard; Thomas F Patterson
Journal:  Clin Infect Dis       Date:  2008-02-01       Impact factor: 9.079

Review 3.  Conventional or molecular measurement of Aspergillus load.

Authors:  K V Clemons; D A Stevens
Journal:  Med Mycol       Date:  2008-07-24       Impact factor: 4.076

4.  First determination of azole resistance in Aspergillus fumigatus strains carrying the TR34/L98H mutations in Turkey.

Authors:  Gülşah Ece Özmerdiven; Seçil Ak; Beyza Ener; Harun Ağca; Burcu Dalyan Cilo; Berrin Tunca; Halis Akalın
Journal:  J Infect Chemother       Date:  2015-05-14       Impact factor: 2.211

5.  Epidemiology and outcomes of invasive fungal infections in allogeneic haematopoietic stem cell transplant recipients in the era of antifungal prophylaxis: a single-centre study with focus on emerging pathogens.

Authors:  Dora E Corzo-León; Michael J Satlin; Rosemary Soave; Tsiporah B Shore; Audrey N Schuetz; Samantha E Jacobs; Thomas J Walsh
Journal:  Mycoses       Date:  2015-03-24       Impact factor: 4.377

6.  Emergence of azole-resistant invasive aspergillosis in HSCT recipients in Germany.

Authors:  J Steinmann; A Hamprecht; M J G T Vehreschild; O A Cornely; D Buchheidt; B Spiess; M Koldehoff; J Buer; J F Meis; P-M Rath
Journal:  J Antimicrob Chemother       Date:  2015-01-27       Impact factor: 5.790

7.  Epidemiological trends in invasive aspergillosis in France: the SAIF network (2005-2007).

Authors:  O Lortholary; J-P Gangneux; K Sitbon; B Lebeau; F de Monbrison; Y Le Strat; B Coignard; F Dromer; S Bretagne
Journal:  Clin Microbiol Infect       Date:  2011-06-10       Impact factor: 8.067

8.  Azole resistance in Aspergillus fumigatus isolates from the ARTEMIS global surveillance study is primarily due to the TR/L98H mutation in the cyp51A gene.

Authors:  Shawn R Lockhart; João P Frade; Kizee A Etienne; Michael A Pfaller; Daniel J Diekema; S Arunmozhi Balajee
Journal:  Antimicrob Agents Chemother       Date:  2011-06-20       Impact factor: 5.191

9.  Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group.

Authors:  Ben De Pauw; Thomas J Walsh; J Peter Donnelly; David A Stevens; John E Edwards; Thierry Calandra; Peter G Pappas; Johan Maertens; Olivier Lortholary; Carol A Kauffman; David W Denning; Thomas F Patterson; Georg Maschmeyer; Jacques Bille; William E Dismukes; Raoul Herbrecht; William W Hope; Christopher C Kibbler; Bart Jan Kullberg; Kieren A Marr; Patricia Muñoz; Frank C Odds; John R Perfect; Angela Restrepo; Markus Ruhnke; Brahm H Segal; Jack D Sobel; Tania C Sorrell; Claudio Viscoli; John R Wingard; Theoklis Zaoutis; John E Bennett
Journal:  Clin Infect Dis       Date:  2008-06-15       Impact factor: 9.079

10.  Frequency and evolution of Azole resistance in Aspergillus fumigatus associated with treatment failure.

Authors:  Susan J Howard; Dasa Cerar; Michael J Anderson; Ahmed Albarrag; Matthew C Fisher; Alessandro C Pasqualotto; Michel Laverdiere; Maiken C Arendrup; David S Perlin; David W Denning
Journal:  Emerg Infect Dis       Date:  2009-07       Impact factor: 6.883
View more
  6 in total

Review 1.  Aspergillus fumigatus and aspergillosis: From basics to clinics.

Authors:  A Arastehfar; A Carvalho; J Houbraken; L Lombardi; R Garcia-Rubio; J D Jenks; O Rivero-Menendez; R Aljohani; I D Jacobsen; J Berman; N Osherov; M T Hedayati; M Ilkit; D James-Armstrong; T Gabaldón; J Meletiadis; M Kostrzewa; W Pan; C Lass-Flörl; D S Perlin; M Hoenigl
Journal:  Stud Mycol       Date:  2021-05-10       Impact factor: 16.097

2.  Five-Year Survey (2014 to 2018) of Azole Resistance in Environmental Aspergillus fumigatus Isolates from China.

Authors:  Duantao Cao; Ruilin Wu; Suxia Dong; Feiyan Wang; Chao Ju; Sumei Yu; Shiji Xu; Hua Fang; Yunlong Yu
Journal:  Antimicrob Agents Chemother       Date:  2020-09-21       Impact factor: 5.191

3.  The fading boundaries between patient and environmental routes of triazole resistance selection in Aspergillus fumigatus.

Authors:  Jochem B Buil; Rasmus K Hare; Bas J Zwaan; Maiken C Arendrup; Willem J G Melchers; Paul E Verweij
Journal:  PLoS Pathog       Date:  2019-08-22       Impact factor: 6.823

4.  Invasive Fungal Infections 2021.

Authors:  Immaculata Xess; Livio Pagano; Yubhisha Dabas
Journal:  J Fungi (Basel)       Date:  2022-07-22

5.  Point Mutations in the 14-α Sterol Demethylase Cyp51A or Cyp51C Could Contribute to Azole Resistance in Aspergillus flavus.

Authors:  Jose Lucio; Irene Gonzalez-Jimenez; Olga Rivero-Menendez; Ana Alastruey-Izquierdo; Teresa Pelaez; Laura Alcazar-Fuoli; Emilia Mellado
Journal:  Genes (Basel)       Date:  2020-10-17       Impact factor: 4.096

6.  Epidemiology and Antifungal Susceptibility Patterns of Invasive Fungal Infections (IFIs) in India: A Prospective Observational Study.

Authors:  Yubhisha Dabas; Immaculata Xess; Mragnayani Pandey; Jaweed Ahmed; Janya Sachdev; Azka Iram; Gagandeep Singh; Manoranjan Mahapatra; Rachna Seth; Sameer Bakhshi; Rakesh Kumar; Viveka P Jyotsna; Sandeep Mathur
Journal:  J Fungi (Basel)       Date:  2021-12-30
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.