| Literature DB >> 29889763 |
Giuseppe Chiossi1, George R Saade, Baha Sibai, Vincenzo Berghella.
Abstract
Spontaneous preterm birth is a leading cause of perinatal morbidity and mortality; however, accurate identification of women who will deliver prematurely after the onset of uterine contractions is still challenging, because less than 10% actually give birth within 7 days of presentation. Risk stratification in women with preterm contractions would allow targeting of interventions such as corticosteroids, magnesium sulfate, and maternal transfer to a perinatal center to those who will indeed deliver preterm. Moreover, unnecessary treatments associated with potential complications could be avoided in symptomatic women who are unlikely to deliver preterm. Fetal fibronectin testing and cervical length measurement are the most used methods to assess the risk of preterm birth among symptomatic women. Interventional studies in singleton gestations suggest that assessment of cervical length, unlike fetal fibronectin testing, improves diagnostic accuracy and leads to better perinatal outcomes.Entities:
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Year: 2018 PMID: 29889763 DOI: 10.1097/AOG.0000000000002695
Source DB: PubMed Journal: Obstet Gynecol ISSN: 0029-7844 Impact factor: 7.661