Literature DB >> 29889033

Disseminated Multi-system Sarcoidosis Mimicking Metastases on 18F-FDG PET/CT.

William Makis1, Mark Palayew2, Christopher Rush2, Stephan Probst2.   

Abstract

A 60-year-old female with no significant medical history presented with hematuria. A computed tomography (CT) scan revealed extensive lymphadenopathy with hypodensities in the liver and spleen, and she was referred for an 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/CT (PET/CT) study to assess for malignancy of unknown primary. PET/CT revealed extensive 18F-FDG avid lymphadenopathy as well as innumerable intensely 18F-FDG avid lung, liver and splenic nodules, highly concerning for malignancy. A PET-guided bone marrow biopsy of the posterior superior iliac spine revealed several non-necrotizing, well-formed granulomas, consistent with sarcoidosis. The patient was managed conservatively and remained clinically well over the subsequent 9 years of follow-up.

Entities:  

Keywords:  18F-fluorodeoxyglucose positron emission tomography.; Sarcoidosis; artifact; lymphadenopathy; metastases; mimic

Year:  2018        PMID: 29889033      PMCID: PMC5996599          DOI: 10.4274/mirt.29200

Source DB:  PubMed          Journal:  Mol Imaging Radionucl Ther


  12 in total

1.  FDG PET in the clinical evaluation of sarcoidosis with bone lesions.

Authors:  A Kobayashi; T Shinozaki; Y Shinjyo; K Kato; N Oriuchi; H Watanabe; K Takagishi
Journal:  Ann Nucl Med       Date:  2000-08       Impact factor: 2.668

2.  FDG positron emission tomography of bone involvement in sarcoidosis.

Authors:  Caroline Aberg; Fabio Ponzo; Bruce Raphael; Edward Amorosi; Victor Moran; Elissa Kramer
Journal:  AJR Am J Roentgenol       Date:  2004-04       Impact factor: 3.959

3.  FDG PET of primary benign and malignant bone tumors: standardized uptake value in 52 lesions.

Authors:  J Aoki; H Watanabe; T Shinozaki; K Takagishi; H Ishijima; N Oya; N Sato; T Inoue; K Endo
Journal:  Radiology       Date:  2001-06       Impact factor: 11.105

4.  Chronic vascular graft infection with fistula to bone causing vertebral osteomyelitis, imaged with F-18 FDG PET/CT.

Authors:  William Makis; Jerry Stern
Journal:  Clin Nucl Med       Date:  2010-10       Impact factor: 7.794

Review 5.  Normal physiological and benign pathological variants of 18-fluoro-2-deoxyglucose positron-emission tomography scanning: potential for error in interpretation.

Authors:  G J Cook; I Fogelman; M N Maisey
Journal:  Semin Nucl Med       Date:  1996-10       Impact factor: 4.446

Review 6.  18-fluorodeoxyglucose positron emission tomographic imaging in the detection and monitoring of infection and inflammation.

Authors:  Hongming Zhuang; Abass Alavi
Journal:  Semin Nucl Med       Date:  2002-01       Impact factor: 4.446

Review 7.  FDG PET imaging in sarcoidosis.

Authors:  Dragana Sobic-Saranovic; Vera Artiko; Vladimir Obradovic
Journal:  Semin Nucl Med       Date:  2013-11       Impact factor: 4.446

8.  Nodular sarcoidosis of the liver and spleen: analysis of 32 cases.

Authors:  D M Warshauer; P L Molina; S M Hamman; R E Koehler; E K Paulson; R E Bechtold; M L Perlmutter; J N Hiken; I R Francis; C J Cooper
Journal:  Radiology       Date:  1995-06       Impact factor: 11.105

9.  Results of 188 whole-body fluorodeoxyglucose positron emission tomography scans in 137 patients with sarcoidosis.

Authors:  Alvin S Teirstein; Josef Machac; Orlandino Almeida; Ping Lu; Maria L Padilla; Michael C Iannuzzi
Journal:  Chest       Date:  2007-10-09       Impact factor: 9.410

Review 10.  Functional imaging in extrapulmonary sarcoidosis: FDG-PET/CT and MR features.

Authors:  Michael Soussan; Alexandre Augier; Pierre-Yves Brillet; Pierre Weinmann; Dominique Valeyre
Journal:  Clin Nucl Med       Date:  2014-02       Impact factor: 7.794

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  3 in total

Review 1.  The impact of infection and inflammation in oncologic 18F-FDG PET/CT imaging.

Authors:  W Tania Rahman; Daniel J Wale; Benjamin L Viglianti; Danyelle M Townsend; Matthew S Manganaro; Milton D Gross; Ka Kit Wong; Domenico Rubello
Journal:  Biomed Pharmacother       Date:  2019-07-01       Impact factor: 6.529

Review 2.  Osseous manifestations of sarcoidosis.

Authors:  Eugeniusz Józef Kucharz
Journal:  Reumatologia       Date:  2020-04-30

Review 3.  Acute Findings on FDG PET/CT: Key Imaging Features and How to Differentiate Them from Malignancy.

Authors:  Yan Li; Spencer Behr
Journal:  Curr Radiol Rep       Date:  2020-09-12
  3 in total

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