Literature DB >> 29888917

N-Heterocyclic Carbene-Catalyzed Asymmetric Benzoin Reaction in Water.

Jun Yan1, Rong Sun1, Kuangxi Shi1, Kai Li1, Limin Yang1, Guofu Zhong1.   

Abstract

A chiral N-heterocyclic carbene-catalyzed benzoin condensation reaction in water has been developed, affording α-hydroxy ketones in good to high yields and high enantioselectivities. Water was proposed as a proton shuttle in the aqueous asymmetric condensation reaction.

Entities:  

Year:  2018        PMID： 29888917     DOI： 10.1021/acs.joc.8b00481

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  3 in total

1.  Bio-inspired NHC-organocatalyzed Stetter reaction in aqueous conditions.

Authors:  Mégane Debiais; Aladin Hamoud; Reihana Drain; Philippe Barthélémy; Valérie Desvergnes
Journal:  RSC Adv       Date:  2020-11-09       Impact factor: 4.036

2.  Desymmetrization of N-Cbz glutarimides through N-heterocyclic carbene organocatalysis.

Authors:  Zhouli Hu; Chenlong Wei; Qianqian Shi; Xianfang Hong; Jinhua Liu; Xiangui Zhou; Jinna Han; Wei Cao; Ashis Kumar Gupta; Xiaoxiang Zhang; Donghui Wei; Zhenqian Fu; Wei Huang
Journal:  Nat Commun       Date:  2022-07-13       Impact factor: 17.694

Review 3.  Enabling protein-hosted organocatalytic transformations.

Authors:  Alexander R Nödling; Nicolò Santi; Thomas L Williams; Yu-Hsuan Tsai; Louis Y P Luk
Journal:  RSC Adv       Date:  2020-04-23       Impact factor: 4.036
  3 in total

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