Xiaoqi Geng1,2, Xiaoyu Liu1,2, Wei Wei3, Yawei Wang1,2, Lizhen Wang1,2, Kinon Chen1,2, Hongqiang Huo1,2, Yuanjie Zhu1,2, Yubo Fan1,2,4. 1. Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, Beijing, China. 2. Beijing Advanced Innovation Centre for Biomedical Engineering, Beihang University, Beijing, China. 3. Department of Ophthalmology, Peking University Third Hospital, Beijing, China. 4. National Research Center for Rehabilitation Technical Aids, Beijing, China.
Abstract
PURPOSE: To evaluate retinal damage as the result of craniomaxillofacial trauma and explain its pathogenic mechanism using finite element (FE) simulation. METHODS: Computed tomography (CT) images of an adult man were obtained to construct a FE skull model. A FE skin model was built to cover the outer surface of the skull model. A previously validated FE right eye model was symmetrically copied to create a FE left eye model, and both eye models were assembled to the skull model. An orbital fat model was developed to fill the space between the eye models and the skull model. Simulations of a ball-shaped object striking the frontal bone, temporal bone, brow, and cheekbones were performed, and the resulting absorption of the impact energy, intraocular pressure (IOP), and strains on the macula and ora serrata were analyzed to evaluate retinal injuries. RESULTS: Strain was concentrated in the macular regions (0.18 in average) of both eyes when the frontal bone was struck. The peak strain on the macula of the struck-side eye was higher than that of the other eye (>100%) when the temporal bone was struck, whereas there was little difference (<10%) between the two eyes when the brow and cheekbones were struck. Correlation analysis showed that the retinal strain time histories were highly correlated with the IOP time histories (r > 0.8 and P = 0.000 in all simulation cases). CONCLUSIONS: The risk of retinal damage is variable in craniomaxillofacial trauma depending on the struck region, and the damage is highly related to IOP variation caused by indirect blunt eye trauma. TRANSLATIONAL RELEVANCE: This finite element eye model allows us to evaluate and understand the indirect ocular injury mechanisms in craniomaxillofacial trauma for better clinical diagnosis and treatment.
PURPOSE: To evaluate retinal damage as the result of craniomaxillofacial trauma and explain its pathogenic mechanism using finite element (FE) simulation. METHODS: Computed tomography (CT) images of an adult man were obtained to construct a FE skull model. A FE skin model was built to cover the outer surface of the skull model. A previously validated FE right eye model was symmetrically copied to create a FE left eye model, and both eye models were assembled to the skull model. An orbital fat model was developed to fill the space between the eye models and the skull model. Simulations of a ball-shaped object striking the frontal bone, temporal bone, brow, and cheekbones were performed, and the resulting absorption of the impact energy, intraocular pressure (IOP), and strains on the macula and ora serrata were analyzed to evaluate retinal injuries. RESULTS: Strain was concentrated in the macular regions (0.18 in average) of both eyes when the frontal bone was struck. The peak strain on the macula of the struck-side eye was higher than that of the other eye (>100%) when the temporal bone was struck, whereas there was little difference (<10%) between the two eyes when the brow and cheekbones were struck. Correlation analysis showed that the retinal strain time histories were highly correlated with the IOP time histories (r > 0.8 and P = 0.000 in all simulation cases). CONCLUSIONS: The risk of retinal damage is variable in craniomaxillofacial trauma depending on the struck region, and the damage is highly related to IOP variation caused by indirect blunt eye trauma. TRANSLATIONAL RELEVANCE: This finite element eye model allows us to evaluate and understand the indirect ocular injury mechanisms in craniomaxillofacial trauma for better clinical diagnosis and treatment.
Authors: Basem T Jamal; Scott M Pfahler; Kate A Lane; Jurj R Bilyk; Edmund A Pribitkin; Robert J Diecidue; Daniel I Taub Journal: J Oral Maxillofac Surg Date: 2009-05 Impact factor: 1.895
Authors: William J Foster; Brian W Berg; Steven N Luminais; Amir Hadayer; Shlomit Schaal Journal: Am J Ophthalmol Date: 2022-03-28 Impact factor: 5.488