Literature DB >> 29887701

Right and Transverse Colonic Multi-Visceral Resections for Locally Advanced Cancers-a Single-Center Experience.

Joseph Sebastian1, Mohamed Boshnaq1,2, Mohanraj Harilingam1, Chukwuemeka Anele1, Mansoor Akhtar1, Deya Marzouk1.   

Abstract

Locally advanced colorectal tumors constitute to about 5-22% of all colorectal cancers at the time of presentation. Multi-visceral resection is usually required for such cases in order to achieve curative resection (R0). We aim to present our experience of right and transverse colonic en bloc resections and their outcomes. Retrospective review of a prospective database between February 2008 and December 2014. Case notes, operative findings, histopathology results, and follow-up records were analyzed. A total of 23 patients underwent en bloc multi-visceral resections for locally advanced right-sided or transverse colonic cancers. There were 11 males and 12 females. The mean age was 75 years. Fifteen patients were operated electively and eight were done as emergency. Median follow-up was 36 months. Eleven out of 23 (47%) had more than one organ resected. 78.3% had R0 resections, 17.4% were R1, and 4.3% were indeterminate. The average lymph node yield was 22 [range 5-45]. Senior trainees under supervision did 65% of procedures. Twelve-month disease-free survival was 90% and the 5-year survival was 65%. Right-sided and transverse colonic tumors have a propensity to become locally advanced making curative resections challenging. This is especially relevant when these patients present as an emergency or if the surgeon is less experienced and may opt for a palliative procedure, thus leading to suboptimal outcomes. Multi-visceral resections for locally advanced tumors can be feasible in the district general hospital setting with acceptable outcomes. Multi-disciplinary meeting (MDM) process, adequate training, and experience are vital.

Entities:  

Keywords:  En bloc resection; Locally advanced colorectal tumors; Multi-visceral resections

Year:  2018        PMID: 29887701      PMCID: PMC5984872          DOI: 10.1007/s13193-018-0762-6

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  20 in total

1.  Multivisceral resections for colorectal cancer.

Authors:  M J Lopez
Journal:  J Surg Oncol       Date:  2001-01       Impact factor: 3.454

2.  Practice parameters for colon cancer.

Authors:  Daniel Otchy; Neil H Hyman; Clifford Simmang; Thomas Anthony; W Donald Buie; Peter Cataldo; James Church; Jeffrey Cohen; Frederick Dentsman; C Neal Ellis; John W Kilkenny; Clifford Ko; Richard Moore; Charles Orsay; Ronald Place; Janice Rafferty; Jan Rakinic; Paul Savoca; Joe Tjandra; Mark Whiteford
Journal:  Dis Colon Rectum       Date:  2004-08       Impact factor: 4.585

3.  Multivisceral resection for locally advanced primary colon and rectal cancer: an analysis of prognostic factors in 201 patients.

Authors:  Thomas Lehnert; Mascha Methner; Andreas Pollok; Anja Schaible; Ulf Hinz; Christian Herfarth
Journal:  Ann Surg       Date:  2002-02       Impact factor: 12.969

4.  Multi-organ resections for colorectal cancer: analysis of potential factors with role in the occurrence of postoperative complications and deaths.

Authors:  A Bartoş; D Bartoş; F Dunca; L Mocanu; F Zaharie; M Iancu; A Mironiuc; C Iancu
Journal:  Chirurgia (Bucur)       Date:  2012 Jul-Aug

5.  Multivisceral resection of advanced colorectal carcinoma.

Authors:  C Gebhardt; W Meyer; S Ruckriegel; U Meier
Journal:  Langenbecks Arch Surg       Date:  1999-04       Impact factor: 3.445

6.  En bloc resection of right-sided colonic adenocarcinoma with adjacent organ invasion.

Authors:  Sorabh Kapoor; Biswabasu Das; Sujoy Pal; Peush Sahni; Tushar K Chattopadhyay
Journal:  Int J Colorectal Dis       Date:  2005-06-07       Impact factor: 2.571

Review 7.  Role of extended resection in the initial treatment of locally advanced colorectal carcinoma.

Authors:  M J Lopez; W W Monafo
Journal:  Surgery       Date:  1993-04       Impact factor: 3.982

8.  Prognostic groups in colorectal carcinoma.

Authors:  P Hermanek; F P Gall; A Altendorf
Journal:  J Cancer Res Clin Oncol       Date:  1980       Impact factor: 4.553

9.  Radical resection of locally advanced colorectal cancer.

Authors:  M Poeze; J G Houbiers; C J van de Velde; T Wobbes; M F von Meyenfeldt
Journal:  Br J Surg       Date:  1995-10       Impact factor: 6.939

10.  En Bloc Pancreaticoduodenectomy for Locally Advanced Right Colon Cancers.

Authors:  Cihan Ağalar; Aras Emre Canda; Tarkan Unek; Selman Sokmen
Journal:  Int J Surg Oncol       Date:  2017-07-02
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