Literature DB >> 29887422

The clinical and biological impacts of the implementation of fast-track perioperative programs in complex liver resections: A propensity score-based analysis between the open and laparoscopic approaches.

Francesca Ratti1, Federica Cipriani2, Raffaella Reineke3, Laura Comotti3, Michele Paganelli2, Marco Catena2, Luigi Beretta3, Luca Aldrighetti2.   

Abstract

BACKGROUND: The aim of this study was to evaluate the impact of the fast-track approach in patients undergoing complex liver procedures and to analyse factors that influence morbidity and functional recovery.
METHODS: Hepatic resections (2014-2016) were stratified according to difficulty score, obtaining a group of 215 complex resections (102 laparoscopic, 163 open). The laparoscopic group was matched by propensity score with open patients to obtain the minimally invasive liver surgery group (n = 102) and the open group (n = 102).
RESULTS: Groups were similar in terms of patient and disease characteristics. The postoperative morbidity was 31.4% in the minimally invasive liver surgery and 38.2% in the open group (P = .05), and functional recovery was shorter in the minimally invasive liver surgery (respectively 4 versus 6 days, P = .041). The adherence to fast-track was high in both groups, with several items with higher penetrance in the minimally invasive liver surgery group. Among factors associated with morbidity and functional recovery, a laparoscopic approach and strict adherence to a fast-track protocol resulted in protective factors.
CONCLUSION: The combination of minimally invasive approaches and fast-track protocols allows a reduced rate of postoperative morbidity and satisfactory functional recovery even in the setting of complex liver resections. When the laparoscopic approach is not feasible, strict adherence to a fast-track program is associated with the achievement of adequate results and should be implemented.
Copyright © 2018 Elsevier Inc. All rights reserved.

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Year:  2018        PMID: 29887422     DOI: 10.1016/j.surg.2018.04.020

Source DB:  PubMed          Journal:  Surgery        ISSN: 0039-6060            Impact factor:   3.982


  4 in total

1.  Timing of Perioperative Chemotherapy Does Not Influence Long-Term Outcome of Patients Undergoing Combined Laparoscopic Colorectal and Liver Resection in Selected Upfront Resectable Synchronous Liver Metastases.

Authors:  Francesca Ratti; David Fuks; Federica Cipriani; Brice Gayet; Luca Aldrighetti
Journal:  World J Surg       Date:  2019-12       Impact factor: 3.352

2.  Vascular occlusion to protect against intraoperative blood loss in liver surgeries: new perspectives on a traditional technique.

Authors:  Francesca Ratti; Alessandro Nini; Roberto Bertini; Luca Aldrighetti
Journal:  Hepatobiliary Surg Nutr       Date:  2021-08       Impact factor: 7.293

3.  Have we really understood when the efforts of laparoscopic liver resection are justified?-a complexity-based appraisal of the differential benefit.

Authors:  Francesca Ratti; Federica Cipriani; Guido Fiorentini; Marco Catena; Michele Paganelli; Luca Aldrighetti
Journal:  Hepatobiliary Surg Nutr       Date:  2022-06       Impact factor: 8.265

Review 4.  ERAS in minimally invasive hepatectomy.

Authors:  Andrew K Y Fung; Charing C N Chong; Paul B S Lai
Journal:  Ann Hepatobiliary Pancreat Surg       Date:  2020-05-31
  4 in total

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