Joanna Miłkowska-Dymanowska1, Adam J Białas1, Waldemar Obrębski1, Paweł Górski1, Wojciech J Piotrowski2. 1. Department of Pneumology and Allergy, Medical University of Łódź, Poland; Healthy Ageing Research Centre (HARC), Medical University of Łódź, Poland. 2. Department of Pneumology and Allergy, Medical University of Łódź, Poland; Healthy Ageing Research Centre (HARC), Medical University of Łódź, Poland. Electronic address: wojciech.piotrowski@umed.lodz.pl.
Abstract
BACKGROUND: Exacerbations of COPD (ECOPD) are important events in the course of COPD and they accelerate the rate of decline of lung function, and exacerbations requiring hospitalization are associated with significant mortality. Therefore, developing approaches of prevention and early treatment of ECOPDs are of special clinical interests. One of such approaches is telecare, including home telemonitoring. MATERIAL AND METHODS: Daily telemonitoring of HR, BP, SpO2 and spirometry was performed. Variables were compared using the bootstrap-boosted inference tests: the paired t-test or Wilcoxon signed rank test, depending on data normality, and categorical variables were compared using exact McNemar's test. RESULTS: Nineteen patients were included to the study. We observed significant decrease in SpO2 7 days preceding ECOPD (P = 0.007; Pbootstrap-boosted = 0.005) and increase in number of events of day-to-day decrease in oxygen saturation >4% in the period of 7 days preceding ECOPD versus reference period (P = 0.02). CONCLUSIONS: Oxygen saturation telemonitoring would be successfully used in predicting ECOPD. Recording of day-to-day decrease in oxygen saturation >4% as alarming events would be effective approach which would be easily implemented in telemonitoring devices, however this outcome should be further validated in larger size samples.
BACKGROUND: Exacerbations of COPD (ECOPD) are important events in the course of COPD and they accelerate the rate of decline of lung function, and exacerbations requiring hospitalization are associated with significant mortality. Therefore, developing approaches of prevention and early treatment of ECOPDs are of special clinical interests. One of such approaches is telecare, including home telemonitoring. MATERIAL AND METHODS: Daily telemonitoring of HR, BP, SpO2 and spirometry was performed. Variables were compared using the bootstrap-boosted inference tests: the paired t-test or Wilcoxon signed rank test, depending on data normality, and categorical variables were compared using exact McNemar's test. RESULTS: Nineteen patients were included to the study. We observed significant decrease in SpO2 7 days preceding ECOPD (P = 0.007; Pbootstrap-boosted = 0.005) and increase in number of events of day-to-day decrease in oxygen saturation >4% in the period of 7 days preceding ECOPD versus reference period (P = 0.02). CONCLUSIONS:Oxygen saturation telemonitoring would be successfully used in predicting ECOPD. Recording of day-to-day decrease in oxygen saturation >4% as alarming events would be effective approach which would be easily implemented in telemonitoring devices, however this outcome should be further validated in larger size samples.
Authors: Grace Hawthorne; Matthew Richardson; Neil J Greening; Dale Esliger; Samuel Briggs-Price; Emma J Chaplin; Lisa Clinch; Michael C Steiner; Sally J Singh; Mark W Orme Journal: Respir Res Date: 2022-04-26
Authors: Joren Buekers; Jan Theunis; Patrick De Boever; Anouk W Vaes; Maud Koopman; Eefje Vm Janssen; Emiel Fm Wouters; Martijn A Spruit; Jean-Marie Aerts Journal: JMIR Mhealth Uhealth Date: 2019-06-06 Impact factor: 4.773
Authors: Grace Hawthorne; Neil Greening; Dale Esliger; Samuel Briggs-Price; Matthew Richardson; Emma Chaplin; Lisa Clinch; Michael C Steiner; Sally J Singh; Mark W Orme Journal: JMIR Hum Factors Date: 2022-02-16