Literature DB >> 29886468

[Causes and management for male urethral stricture].

Caifang Chen1, Mingqiang Zeng2, Ruizhi Xue3, Guilin Wang3, Zhiyong Gao4, Wuxiong Yuan4, Zhengyan Tang3.   

Abstract

OBJECTIVE: To explore the etiology of male urethral stricture, analyze the therapeutic strategies of urethral stricture, and summarize the complicated cases.

Methods: The data of 183 patients with urethral stricture were retrospectively analyzed, including etiology, obstruction site, stricture length, therapeutic strategy, and related complications.

Results: The mean age was 49.7 years, the average course was 64.7 months, and the constituent ratio of 51 to 65 years old patients was 38.8% (71/183). The traumatic injury of patients accounted for 52.4% (96/183), in which the pelvic fracture accounted for 35.5% (65/183) and the straddle injury accounted for 16.9% (31/183). There were 54 cases of iatrogenic injury (29.5%). The posterior urethral stricture accounted for 45.9% (84/183), followed by the anterior urethral stricture (44.8%, 82/183) and the stenosis (6.6%, 12/183). A total of 99 patients (54.1%) received the end to end anastomosis, and 40 (21.9%) were treated with intracavitary surgery, such as endoscopic holmium laser, cold knife incision, endoscopic electroknife scar removal, balloon dilation, and urethral dilation. In the patients over 65-years old, the urethral stricture rate was 14.8% and the complication rate (70.4%) for transurethral resection of the prostate (TURP) was significantly higher than that of all samples (P<0.01).

Conclusion: Both the etiology of male urethral stricture and the treatment strategy have changed and the incidence of traumatic and iatrogenic urethral stricture has increased in recent 3 years. The main treatment of urethral stricture has been transformed from endoscopic surgery into urethroplasty.

Entities:  

Mesh:

Year:  2018        PMID: 29886468     DOI: 10.11817/j.issn.1672-7347.2018.05.010

Source DB:  PubMed          Journal:  Zhong Nan Da Xue Xue Bao Yi Xue Ban        ISSN: 1672-7347


  2 in total

1.  The effect of intraurethral hyaluronic acid on healing and fibrosis in rats with experimentally induced urethral trauma.

Authors:  Engin Doğantekin; Turgay Akgül; Eylem Pınar Eser; Mustafa Kotanoğlu; Veysel Bayburtluoğlu; Sema Hücümenoğlu
Journal:  Int Urol Nephrol       Date:  2022-01-31       Impact factor: 2.370

2.  Exploring Relevant mRNAs and miRNAs in Injured Urethral Tissues of Rats with High-Throughput Sequencing.

Authors:  Han Lin; Shiyong Guo; Song Li; Jihong Shen; Jianfeng He; Yun Zheng; Zhenhua Gao
Journal:  Genes (Basel)       Date:  2022-05-05       Impact factor: 4.141

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.