Javad Yazdani1, Elham Ahmadian2, Simin Sharifi2, Shahriar Shahi3, Solmaz Maleki Dizaj4. 1. Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran. 2. Dental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. 3. Dental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Faculty of Dentistry, Department of Endodontics, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: shahis@tbzmed.ac.ir. 4. Dental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: Maleki.s@tbzmed.ac.ir.
Abstract
INTRODUCTION: Titanium based (Ti-based) materials have been used as dental implants due to their high biocompatibility, good mechanical strength and ideal osseointegration properties. Osseointegration of an implant is dependent on surface characteristics such as surface chemistry and topography. Nanotechnology has presented new and interesting applications in dentistry in recent years. The presence of nanoparticles on the implant surface can affect both the topography and surface chemistry, leading to different and outstanding specifications for implant. METHOD: A literature review was performed in electronic databases by means of MeSH keywords to collect relevant published literature in English about the effect of nanohydroxyapatite on osseointegration of titanium implants. No limitations on publication date were imposed. Data regarding titanium implants; nanotechnology; nanohydroxyapatite; osseointegration and cell attachment were collected and reviewed. RESULTS AND CONCLUSION: According to reviewed literature, nanohydroxyapatites have a nanostructured surface with higher surface area and then higher reactivity, letting them to bind to bone creating a biomimetic coating on implants. However, more studies are needed on the cell-substrate interface to develop an effective implant due to the interaction of the cells and the biomaterial surface after the implantation.
INTRODUCTION:Titanium based (Ti-based) materials have been used as dental implants due to their high biocompatibility, good mechanical strength and ideal osseointegration properties. Osseointegration of an implant is dependent on surface characteristics such as surface chemistry and topography. Nanotechnology has presented new and interesting applications in dentistry in recent years. The presence of nanoparticles on the implant surface can affect both the topography and surface chemistry, leading to different and outstanding specifications for implant. METHOD: A literature review was performed in electronic databases by means of MeSH keywords to collect relevant published literature in English about the effect of nanohydroxyapatite on osseointegration of titanium implants. No limitations on publication date were imposed. Data regarding titanium implants; nanotechnology; nanohydroxyapatite; osseointegration and cell attachment were collected and reviewed. RESULTS AND CONCLUSION: According to reviewed literature, nanohydroxyapatites have a nanostructured surface with higher surface area and then higher reactivity, letting them to bind to bone creating a biomimetic coating on implants. However, more studies are needed on the cell-substrate interface to develop an effective implant due to the interaction of the cells and the biomaterial surface after the implantation.