Literature DB >> 2988625

Comparative analysis of the human and feline c-sis proto-oncogenes. Identification of 5' human c-sis coding sequences that are not homologous to the transforming gene of simian sarcoma virus.

A M van den Ouweland, M L Breuer, P H Steenbergh, J A Schalken, H P Bloemers, W J Van de Ven.   

Abstract

Feline and human genetic sequences, homologous to the v-sis gene of simian sarcoma virus, have been isolated from cosmid gene libraries and characterized by restriction endonuclease analysis. Comparison of the two loci revealed their related structural organization. In both loci, similar unique genetic sequences were found upstream of the v-sis homologous region and these hybridized to a 4.2 kbp c-sis transcript in human lung tumor cells. These data establish and map as yet unidentified coding sequences at the 5' part of the c-sis proto-oncogene of both species.

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Year:  1985        PMID： 2988625     DOI： 10.1016/0167-4781(85)90097-1

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  10 in total

1.  fur gene expression as a discriminating marker for small cell and nonsmall cell lung carcinomas.

Authors:  J A Schalken; A J Roebroek; P P Oomen; S S Wagenaar; F M Debruyne; H P Bloemers; W J Van de Ven
Journal:  J Clin Invest       Date:  1987-12       Impact factor: 14.808

2.  Nucleotide sequence of the DNA region immediately upstream of the human c-sis proto-oncogene.

Authors:  A M Van den Ouweland; J J van Groningen; P J Hendriksen; H P Bloemers; W J Van de Ven
Journal:  Nucleic Acids Res       Date:  1987-05-26       Impact factor: 16.971

3.  Expression of proto-oncogenes in xenografts of human renal cell carcinomas.

Authors:  H F Karthaus; M J Bussemakers; J A Schalken; K H Kurth; W F Feitz; F M Debruyne; H P Bloemers; W J Van de Ven
Journal:  Urol Res       Date:  1987

4.  Structure and nucleotide sequence of the 5' region of the human and feline c-sis proto-oncogenes.

Authors:  A M Van den Ouweland; A J Roebroek; J A Schalken; C A Claesen; H P Bloemers; W J Van de Ven
Journal:  Nucleic Acids Res       Date:  1986-01-24       Impact factor: 16.971

5.  Major structural alterations of the c-sis gene are not observed in a series of tumors of the human central nervous system.

Authors:  R D Press; A Misra; D Samols; D A Goldthwait; T B Mapstone
Journal:  J Neurooncol       Date:  1989-11       Impact factor: 4.130

6.  Expression of the human fes cellular oncogene in renal cell tumors.

Authors:  H F Karthaus; J A Schalken; W F Feitz; F M Debruyne; P T de Haan; H P Bloemers; W J Van de Ven
Journal:  Urol Res       Date:  1986

7.  Characterization of human c-fes/fps reveals a new transcription unit (fur) in the immediately upstream region of the proto-oncogene.

Authors:  A J Roebroek; J A Schalken; M J Bussemakers; H van Heerikhuizen; C Onnekink; F M Debruyne; H P Bloemers; W J Van de Ven
Journal:  Mol Biol Rep       Date:  1986       Impact factor: 2.316

8.  A novel human c-sis mRNA species is transcribed from a promoter in c-sis intron 1 and contains the code for an alternative PDGF B-like protein.

Authors:  R P Dirks; C Onnekink; H J Jansen; A de Jong; H P Bloemers
Journal:  Nucleic Acids Res       Date:  1995-08-11       Impact factor: 16.971

9.  In vivo footprinting and functional analysis of the human c-sis/PDGF B gene promoter provides evidence for two binding sites for transcriptional activators.

Authors:  R P Dirks; H J Jansen; B van Gerven; C Onnekink; H P Bloemers
Journal:  Nucleic Acids Res       Date:  1995-04-11       Impact factor: 16.971

10.  Evolutionary conserved close linkage of the c-fes/fps proto-oncogene and genetic sequences encoding a receptor-like protein.

Authors:  A J Roebroek; J A Schalken; J A Leunissen; C Onnekink; H P Bloemers; W J Van de Ven
Journal:  EMBO J       Date:  1986-09       Impact factor: 11.598
  10 in total

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