Literature DB >> 29886169

Structure and gene cluster of the K125 capsular polysaccharide from Acinetobacter baumannii MAR13-1452.

Nikolay P Arbatsky1, Mikhail M Shneider2, Andrei S Dmitrenok1, Anastasia V Popova3, Dmitry A Shagin4, Andrey A Shelenkov4, Yulia V Mikhailova4, Mikhail V Edelstein5, Yuriy A Knirel6.   

Abstract

A capsular polysaccharide (CPS) was isolated from strain MAR13-1452 of an emerging pathogen Acinetobacter baumannii and assigned type K125. The following structure of the CPS was established by sugar analysis, Smith degradation, and 1D and 2D 1H and 13C NMR spectroscopy: Proteins encoded by the KL125 gene cluster in the genome of MAR13-1452, including three glycosyltransferases, were assigned roles in the biosynthesis of the K125 CPS.
Copyright © 2018 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Acinetobacter baumannii; Bacterial polysaccharide structure; Capsular polysaccharide; Capsule biosynthesis; Gene cluster

Mesh：

Substances：

Year:  2018        PMID： 29886169     DOI： 10.1016/j.ijbiomac.2018.06.029

Source DB:  PubMed          Journal:  Int J Biol Macromol        ISSN： 0141-8130            Impact factor:   6.953


  5 in total

1.  K2 Capsule Depolymerase Is Highly Stable, Is Refractory to Resistance, and Protects Larvae and Mice from Acinetobacter baumannii Sepsis.

Authors:  Hugo Oliveira; Ana Mendes; Alexandra G Fraga; Alice Ferreira; Andreia I Pimenta; Dalila Mil-Homens; Arsénio M Fialho; Jorge Pedrosa; Joana Azeredo
Journal:  Appl Environ Microbiol       Date:  2019-08-14       Impact factor: 4.792

2.  The K46 and K5 capsular polysaccharides produced by Acinetobacter baumannii NIPH 329 and SDF have related structures and the side-chain non-ulosonic acids are 4-O-acetylated by phage-encoded O-acetyltransferases.

Authors:  Johanna J Kenyon; Nikolay P Arbatsky; Mikhail M Shneider; Anastasiya V Popova; Andrei S Dmitrenok; Anastasiya A Kasimova; Alexander S Shashkov; Ruth M Hall; Yuriy A Knirel
Journal:  PLoS One       Date:  2019-06-20       Impact factor: 3.240

3.  Specific Interaction of Novel Friunavirus Phages Encoding Tailspike Depolymerases with Corresponding Acinetobacter baumannii Capsular Types.

Authors:  A V Popova; M M Shneider; N P Arbatsky; A A Kasimova; S N Senchenkova; A S Shashkov; A S Dmitrenok; A O Chizhov; Y V Mikhailova; D A Shagin; O S Sokolova; O Y Timoshina; R S Kozlov; K A Miroshnikov; Y A Knirel
Journal:  J Virol       Date:  2020-12-02       Impact factor: 5.103

4.  Identification of Acinetobacter baumannii loci for capsular polysaccharide (KL) and lipooligosaccharide outer core (OCL) synthesis in genome assemblies using curated reference databases compatible with Kaptive.

Authors:  Kelly L Wyres; Sarah M Cahill; Kathryn E Holt; Ruth M Hall; Johanna J Kenyon
Journal:  Microb Genom       Date:  2020-03

5.  Genomic Characterization of Clinical Acinetobacter baumannii Isolates Obtained from COVID-19 Patients in Russia.

Authors:  Andrey Shelenkov; Yulia Mikhaylova; Lyudmila Petrova; Irina Gaidukova; Mikhail Zamyatin; Vasiliy Akimkin
Journal:  Antibiotics (Basel)       Date:  2022-03-06
  5 in total

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