Literature DB >> 29884710

Concomitant sarcoidosis and papillary thyroid cancer with severe hypercalcaemia as the main symptom.

Mikael Groth Riis1, Kasper Svendsen Juhl1, Jens Meldgaard Bruun1,2.   

Abstract

A 65-year-old Caucasian man was admitted to our hospital due to incidental finding of plasma ionised calcium=1.83 mmol/L. During the previous months, he had felt more tired and had experienced an unintended weight loss of 6-8 kg. A CT scan revealed an inhomogeneous thyroid gland and enlarged lymph nodes along the cervical vessels and in the mediastinum. The patient underwent total thyroidectomy and, at the same time, two lymph nodes were removed. Histological examination of the thyroid gland revealed papillary thyroid carcinoma (PTC), T1aN0M0, and histological examination of the lymph nodes showed non-caseating granulomatous inflammation. After further investigation, a diagnosis of sarcoidosis (SA) was made.Coexistence of SA and PTC may yield a diagnostic challenge as both diseases might involve the lymph nodes of the neck. Furthermore, the case illustrates the importance of close follow-up of even moderate hypercalcaemia, since it may evolve into a hypercalcaemic crisis. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  endocrine cancer; immunology; thyroid disease

Mesh:

Year:  2018        PMID: 29884710      PMCID: PMC6011447          DOI: 10.1136/bcr-2017-222194

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  20 in total

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3.  The diagnostic challenge of coexistent sarcoidosis and thyroid cancer - a retrospective study.

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  3 in total

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