Literature DB >> 29884669

Meningovascular syphilis causing recurrent stroke and diagnostic difficulties: a scourge from the past.

Sunil Munshi1, Senthil K Raghunathan1, Ileana Lindeman1, Ashit K Shetty1.   

Abstract

We describe a case of a 49-year-old man who presented with recurrent strokes in the left middle cerebral artery territory, manifesting with dysphasia, higher cognitive deficits, motor deficits and subsequent infarcts in the right middle cerebral and anterior cerebral artery territories, manifesting with seizures, behavioural and social issues. A key issue of the case was the diagnostic difficulty faced by the physicians. 'Meningovascular syphilis' was subsequently confirmed and appropriate treatment was given but there was subsequent relapse with worsening of the symptoms. Multiple specialists were involved in the management, namely stroke team, neurologists, psychiatrists, infectious disease and multidisciplinary therapy teams. This case highlights the need to be vigilant to the resurgence of syphilis, a scourge from the past, as a cause of stroke, especially in individuals who have had exposure to affected people. It is easy to miss the diagnosis and mistake it for other conditions unless a detailed history is taken and appropriate investigations are conducted, with a low threshold for diagnosis. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  infection (neurology); stroke; syphilis

Mesh:

Substances:

Year:  2018        PMID: 29884669      PMCID: PMC6011505          DOI: 10.1136/bcr-2018-225255

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  10 in total

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Journal:  Ther Adv Neurol Disord       Date:  2010-01       Impact factor: 6.570

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Review 4.  REVIEW: Neurosyphilis: A historical perspective and review.

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Authors:  Li-Li Liu; Wei-Hong Zheng; Man-Li Tong; Gui-Li Liu; Hui-Lin Zhang; Zuo-Gen Fu; Li-Rong Lin; Tian-Ci Yang
Journal:  J Neurol Sci       Date:  2012-04-04       Impact factor: 3.181

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Journal:  Eur Neurol       Date:  2004-06-28       Impact factor: 1.710

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Authors:  Christina M Marra
Journal:  Continuum (Minneap Minn)       Date:  2015-12

10.  The great imitator--still today! A case of meningovascular syphilis affecting the posterior circulation.

Authors:  Jochen Bäuerle; Anna Zitzmann; Karl Egger; Stephan Meckel; Cornelius Weiller; Andreas Harloff
Journal:  J Stroke Cerebrovasc Dis       Date:  2014-10-03       Impact factor: 2.136

  10 in total

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