| Literature DB >> 29882413 |
Xiao Meng1, Ban-Ban Li1, Xin Lin1, Yi-Yu Jiang1, Le Zhang1, Hao-Ze Li1, Long Cui1.
Abstract
One new polyacetylene glycoside eprostrata Ⅰ (1), together with seven known compounds (2-8), were isolated from Eclipta prostrata. Their structures were elucidated on the basis of spectroscopic and physico-chemical analyses. All the isolates were evaluated inhibitory activity on DGAT in an in vitro assay. Compounds 1-8 were found to exhibit inhibitory activity of DGAT1 with IC50 values ranging from 74.4 ± 1.3 to 101.1 ± 1.1 μM.Entities:
Keywords: ; Asteraceae; DGAT; polyacetylenic glucosides
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Year: 2018 PMID： 29882413 DOI： 10.1080/10286020.2018.1452914
Source DB: PubMed Journal: J Asian Nat Prod Res ISSN： 1028-6020 Impact factor: 1.569