Literature DB >> 29881169

Minimal clinically important improvement response in patients with severe osteoarthritis of the knee: Short report from a survey of clinicians.

Kristin Salottolo1,2, Eric Stahl3.   

Abstract

The minimal clinically important improvement (MCII) is the smallest change that signifies an important improvement. Disease severity may complicate MCII. We developed an eight-question survey examining MCII in patients with severe knee osteoarthritis (Kellgren-Lawrence grade 4). Twenty-seven of 101 clinicians completed the survey. An MCII of 20% was selected most frequently for pain, function, and patient global assessment. Clinicians were divided on responder rate, selecting 20%, 30%, and 50% equally. These findings suggest a 20% MCII may be useful in patients with severe osteoarthritis, but that there is not enough evidence to support a responder rate in this population.

Entities:  

Keywords:  Kellgren-Lawrence grade; Minimal clinically important improvement; Osteoarthritis

Year:  2018        PMID: 29881169      PMCID: PMC5990343          DOI: 10.1016/j.jor.2018.03.034

Source DB:  PubMed          Journal:  J Orthop        ISSN: 0972-978X


  7 in total

1.  Radiological assessment of osteo-arthrosis.

Authors:  J H KELLGREN; J S LAWRENCE
Journal:  Ann Rheum Dis       Date:  1957-12       Impact factor: 19.103

2.  Minimal clinically important improvement and patient acceptable symptom state for subjective outcome measures in rheumatic disorders.

Authors:  Florence Tubach; Philippe Ravaud; Dorcas Beaton; Maarten Boers; Claire Bombardier; David T Felson; Desireé van der Heijde; George Wells; Maxime Dougados
Journal:  J Rheumatol       Date:  2007-05       Impact factor: 4.666

3.  A randomized placebo-controlled trial of arthroscopic lavage versus lavage plus intra-articular corticosteroids in the management of symptomatic osteoarthritis of the knee.

Authors:  M D Smith; M Wetherall; T Darby; A Esterman; J Slavotinek; P Roberts-Thomson; M Coleman; M J Ahern
Journal:  Rheumatology (Oxford)       Date:  2003-07-16       Impact factor: 7.580

4.  A randomised controlled trial of tidal irrigation vs corticosteroid injection in knee osteoarthritis: the KIVIS Study.

Authors:  N K Arden; I C Reading; K M Jordan; L Thomas; H Platten; A Hassan; J Ledingham
Journal:  Osteoarthritis Cartilage       Date:  2008-02-20       Impact factor: 6.576

5.  Evaluation of clinically relevant changes in patient reported outcomes in knee and hip osteoarthritis: the minimal clinically important improvement.

Authors:  F Tubach; P Ravaud; G Baron; B Falissard; I Logeart; N Bellamy; C Bombardier; D Felson; M Hochberg; D van der Heijde; M Dougados
Journal:  Ann Rheum Dis       Date:  2004-06-18       Impact factor: 19.103

6.  American College of Rheumatology. Preliminary definition of improvement in rheumatoid arthritis.

Authors:  D T Felson; J J Anderson; M Boers; C Bombardier; D Furst; C Goldsmith; L M Katz; R Lightfoot; H Paulus; V Strand
Journal:  Arthritis Rheum       Date:  1995-06

7.  Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations.

Authors:  Robert H Dworkin; Dennis C Turk; Kathleen W Wyrwich; Dorcas Beaton; Charles S Cleeland; John T Farrar; Jennifer A Haythornthwaite; Mark P Jensen; Robert D Kerns; Deborah N Ader; Nancy Brandenburg; Laurie B Burke; David Cella; Julie Chandler; Penny Cowan; Rozalina Dimitrova; Raymond Dionne; Sharon Hertz; Alejandro R Jadad; Nathaniel P Katz; Henrik Kehlet; Lynn D Kramer; Donald C Manning; Cynthia McCormick; Michael P McDermott; Henry J McQuay; Sanjay Patel; Linda Porter; Steve Quessy; Bob A Rappaport; Christine Rauschkolb; Dennis A Revicki; Margaret Rothman; Kenneth E Schmader; Brett R Stacey; Joseph W Stauffer; Thorsten von Stein; Richard E White; James Witter; Stojan Zavisic
Journal:  J Pain       Date:  2007-12-11       Impact factor: 5.820

  7 in total
  1 in total

Review 1.  On the Mechanisms of Action of the Low Molecular Weight Fraction of Commercial Human Serum Albumin in Osteoarthritis.

Authors:  David Bar-Or; Gregory Thomas; Leonard T Rael; Elizabeth Frederick; Melissa Hausburg; Raphael Bar-Or; Edward Brody
Journal:  Curr Rheumatol Rev       Date:  2019
  1 in total

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