T Matsushige1,2,3, M Kraemer4,5, T Sato1,3,6, P Berlit4, M Forsting7, M E Ladd3,8,9, R Jabbarli1, U Sure1, N Khan10, M Schlamann7,11, K H Wrede12,3. 1. From the Department of Neurosurgery (T.M., T.S., R.J., U.S., K.H.W.), University Hospital Essen, University Duisburg-Essen, Essen, Germany. 2. Department of Neurosurgery (T.M.), Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan. 3. Erwin L. Hahn Institute for Magnetic Resonance Imaging (T.M., T.S., M.E.L., K.H.W.), University Duisburg-Essen, Essen, Germany. 4. Department of Neurology (M.K., P.B.), Alfried Krupp Hospital, Essen, Germany. 5. Department of Neurology (M.K.), University Hospital Duesseldorf, Duesseldorf, Germany. 6. Department of Neurosurgery (T.S.), Fukushima Medical University, Fukushima, Japan. 7. Department of Diagnostic and Interventional Radiology and Neuroradiology (M.F., M.S.), University Hospital Essen, Essen, Germany. 8. Medical Physics in Radiology (M.E.L.), German Cancer Research Center, Heidelberg, Germany. 9. Faculty of Physics and Astronomy and Faculty of Medicine (M.E.L.), University of Heidelberg, Heidelberg, Germany. 10. Moyamoya Center, Division of Pediatric Neurosurgery (N.K.), Department of Surgery, University Children's Hospital Zurich, Zurich, Switzerland. 11. Department of Neuroradiology (M.S.), University Hospital Cologne, Cologne, Germany. 12. From the Department of Neurosurgery (T.M., T.S., R.J., U.S., K.H.W.), University Hospital Essen, University Duisburg-Essen, Essen, Germany karsten.wrede@uk-essen.de.
Abstract
BACKGROUND AND PURPOSE: Collateral networks in Moyamoya angiopathy have a complex angioarchitecture difficult to comprehend on conventional examinations. This study aimed to evaluate morphologic patterns and the delineation of deeply seated collateral networks using ultra-high-field MRA in comparison with conventional DSA. MATERIALS AND METHODS: Fifteen white patients with Moyamoya angiopathy were investigated in this prospective trial. Sequences acquired at 7T were TOF-MRA with 0.22 × 0.22 × 0.41 mm3 resolution and MPRAGE with 0.7 × 0.7 × 0.7 mm3 resolution. Four raters evaluated the presence of deeply seated collateral networks and image quality in a consensus reading of DSA, TOF-MRA, and MPRAGE using a 5-point scale in axial source images and maximum intensity projections. Delineation of deeply seated collateral networks by different imaging modalities was compared by means of the McNemar test, whereas image quality was compared using the Wilcoxon signed-rank test. RESULTS: The relevant deeply seated collateral networks were classified into 2 categories and 6 pathways. A total of 100 collateral networks were detected on DSA; 106, on TOF-MRA; and 73, on MPRAGE. Delineation of deeply seated collateral networks was comparable between TOF-MRA and DSA (P = .25); however, both were better than MPRAGE (P < .001). CONCLUSIONS: This study demonstrates excellent delineation of 6 distinct deeply seated collateral network pathways in Moyamoya angiopathy in white adults using 7T TOF-MRA, comparable to DSA.
BACKGROUND AND PURPOSE: Collateral networks in Moyamoya angiopathy have a complex angioarchitecture difficult to comprehend on conventional examinations. This study aimed to evaluate morphologic patterns and the delineation of deeply seated collateral networks using ultra-high-field MRA in comparison with conventional DSA. MATERIALS AND METHODS: Fifteen white patients with Moyamoya angiopathy were investigated in this prospective trial. Sequences acquired at 7T were TOF-MRA with 0.22 × 0.22 × 0.41 mm3 resolution and MPRAGE with 0.7 × 0.7 × 0.7 mm3 resolution. Four raters evaluated the presence of deeply seated collateral networks and image quality in a consensus reading of DSA, TOF-MRA, and MPRAGE using a 5-point scale in axial source images and maximum intensity projections. Delineation of deeply seated collateral networks by different imaging modalities was compared by means of the McNemar test, whereas image quality was compared using the Wilcoxon signed-rank test. RESULTS: The relevant deeply seated collateral networks were classified into 2 categories and 6 pathways. A total of 100 collateral networks were detected on DSA; 106, on TOF-MRA; and 73, on MPRAGE. Delineation of deeply seated collateral networks was comparable between TOF-MRA and DSA (P = .25); however, both were better than MPRAGE (P < .001). CONCLUSIONS: This study demonstrates excellent delineation of 6 distinct deeply seated collateral network pathways in Moyamoya angiopathy in white adults using 7T TOF-MRA, comparable to DSA.
Authors: Byeong Ho Oh; Hyeong Cheol Moon; Hyeon Man Baek; Youn Joo Lee; Sang Woo Kim; Young Jai Jeon; Gun Seok Lee; Hong Rae Kim; Jai Ho Choi; Kyung Soo Min; Mou Seop Lee; Young Gyu Kim; Dong Ho Kim; Won Seop Kim; Young Seok Park Journal: Magn Reson Imaging Date: 2016-11-27 Impact factor: 2.546
Authors: Rachel Kleinloog; Emine Korkmaz; Jaco J M Zwanenburg; Hugo J Kuijf; Fredy Visser; Roos Blankena; Jan A Post; Ynte M Ruigrok; Peter R Luijten; Luca Regli; Gabriel J E Rinkel; Bon H Verweij Journal: Neurosurgery Date: 2014-12 Impact factor: 4.654
Authors: Willem H Bouvy; Geert Jan Biessels; Hugo J Kuijf; L Jaap Kappelle; Peter R Luijten; Jaco J M Zwanenburg Journal: Invest Radiol Date: 2014-05 Impact factor: 6.016
Authors: Annick Kronenburg; Kees P J Braun; Albert van der Zwan; Catharina J M Klijn Journal: Curr Neurol Neurosci Rep Date: 2014-01 Impact factor: 5.081
Authors: Markus Kraemer; Rusen Karakaya; Toshinori Matsushige; Jonas Graf; Philipp Albrecht; Hans-Peter Hartung; Peter Berlit; Rudolf Laumer; Frank Diesner Journal: J Neurol Date: 2018-08-28 Impact factor: 4.849