Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The alpha-spectrin gene is on chromosome 1 in mouse and man.

Literature DB >> 2987946

The alpha-spectrin gene is on chromosome 1 in mouse and man.

K Huebner, A P Palumbo, M Isobe, C A Kozak, S Monaco, G Rovera, C M Croce, P J Curtis.

Abstract

By using alpha-spectrin cDNA clones of murine and human origin and somatic cell hybrids segregating either mouse or human chromosomes, the gene for alpha-spectrin has been mapped to chromosome 1 in both species. This assignment of the mouse alpha-spectrin gene to mouse chromosome 1 by DNA hybridization strengthens the previous identification of the alpha-spectrin locus in mouse with the sph locus, which previously was mapped by linkage analysis to mouse chromosome 1, distal to the Pep-3 locus. By in situ hybridization to human metaphase chromosomes, the human alpha-spectrin gene has been localized to 1q22-1q25; interestingly, the locus for a non-Rh-linked form of elliptocytosis has been provisionally mapped to band 1q2 by family linkage studies.

Entities: Gene Species

Mesh：

Substances：

Year: 1985 PMID： 2987946 PMCID： PMC397873 DOI： 10.1073/pnas.82.11.3790

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

33 in total

1. Localization of spherocytosis to chromosome 8 or 12 and report of a family with spherocytosis and a reciprocal translocation.

Authors: W J Kimberling; T Fulbeck; L Dixon; H A Lubs
Journal: Am J Hum Genet Date: 1975-09 Impact factor: 11.025

2. Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors: E M Southern
Journal: J Mol Biol Date: 1975-11-05 Impact factor: 5.469

3. Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors: P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal: J Mol Biol Date: 1977-06-15 Impact factor: 5.469

Review 4. Spectrin-actin membrane skeleton of normal and abnormal red blood cells.

Authors: S E Lux
Journal: Semin Hematol Date: 1979-01 Impact factor: 3.851

5. Cytological mapping of the genes assigned to the human A 1 chromosome by use of radiation-induced chromosome breakage in a human-Chinese hamster hybrid cell line.

Authors: W Burgerhout; H van Someren; D Bootsma
Journal: Humangenetik Date: 1973

6. Deficiency of skeletal membrane protein band 4.1 in homozygous hereditary elliptocytosis. Implications for erythrocyte membrane stability.

Authors: G Tchernia; N Mohandas; S B Shohet
Journal: J Clin Invest Date: 1981-08 Impact factor: 14.808

7. Gene linkage analysis in the mouse by somatic cell hybridization: assignment of adenine phosphoribosyltransferase to chromosome 8 and alpha-galactosidase to the X chromosome.

Authors: C Kozak; E Nichols; F H Ruddle
Journal: Somatic Cell Genet Date: 1975-10

8. Location on chromosome 1 of Rnr, a gene that regulates renin in the submaxillary gland of the mouse.

Authors: C M Wilson; E G Erdös; J D Wilson; B A Taylor
Journal: Proc Natl Acad Sci U S A Date: 1978-11 Impact factor: 11.205

9. Linkage and gene localization of hereditary spherocytosis (HS).

Authors: W J Kimberling; R A Taylor; R G Chapman; H A Lubs
Journal: Blood Date: 1978-11 Impact factor: 22.113

10. Linkage of isozyyme loci in the mouse: phosphoglucomutase-2 (Pgm-2), mitochondrial NADP malate dehydrogenase (Mod-2), and dipeptidase-1 (Dip-1).

Authors: V M Chapman; F H Ruddle; T H Roderick
Journal: Biochem Genet Date: 1971-04 Impact factor: 1.890

35 in total

1. Inherited haemolytic anaemia created by insertional inactivation of the alpha-spectrin gene.

Authors: G Grimber; C Galand; M Garbarz; M G Mattei; C Cavard; A Zider; P Blanchet; P Boivin; P Briand; D Dhermy
Journal: Transgenic Res Date: 1992-11 Impact factor: 2.788

Review 2. Comparative map for mice and humans.

Authors: J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal: Mamm Genome Date: 1992 Impact factor: 2.957

3. Sp alpha V/41: a common spectrin polymorphism at the alpha IV-alpha V domain junction. Relevance to the expression level of hereditary elliptocytosis due to alpha-spectrin variants located in trans.

Authors: N Alloisio; L Morlé; J Maréchal; A F Roux; M T Ducluzeau; D Guetarni; B Pothier; F Baklouti; A Ghanem; R Kastally; J Delaunay
Journal: J Clin Invest Date: 1991-06 Impact factor: 14.808

Review 4. Mouse map of paralogous genes.

Authors: J H Nadeau; M Kosowsky
Journal: Mamm Genome Date: 1991 Impact factor: 2.957

Review 5. Comparative map for mice and humans.

Authors: J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal: Mamm Genome Date: 1991 Impact factor: 2.957