Literature DB >> 29877089

Asymmetric [4 + 2]-Cycloaddition of Copper-Allenylidenes with Hexahydro-1,3,5-triazines: Access to Chiral Tetrahydroquinazolines.

Danqing Ji1, Cheng Wang1, Jiangtao Sun1.   

Abstract

A copper-catalyzed asymmetric formal [4 + 2]-cycloaddition of copper-allenylidenes and hexahydro-1,3,5-triazines has been developed, providing chiral tetrahydroquinazolines in moderate to good yields and with high enantioselectivities for most cases (up to 88% yield and 98% ee).

Entities:  

Year:  2018        PMID： 29877089     DOI： 10.1021/acs.orglett.8b01584

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  Further Developments and Applications of Oxazoline-Containing Ligands in Asymmetric Catalysis.

Authors:  Robert Connon; Brendan Roche; Balaji V Rokade; Patrick J Guiry
Journal:  Chem Rev       Date:  2021-05-21       Impact factor: 60.622

2.  Two Catalytic Annulation Modes via Cu-Allenylidenes with Sulfur Ylides that Are Dominated by the Presence or Absence of Trifluoromethyl Substituents.

Authors:  Malla Reddy Gannarapu; Jun Zhou; Bingyao Jiang; Norio Shibata
Journal:  iScience       Date:  2020-03-20

Review 3.  An Update of Transition Metal-Catalyzed Decarboxylative Transformations of Cyclic Carbonates and Carbamates.

Authors:  Linhong Zuo; Teng Liu; Xiaowei Chang; Wusheng Guo
Journal:  Molecules       Date:  2019-10-31       Impact factor: 4.411
  3 in total

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