Literature DB >> 29872115

Biochemical mechanisms implemented by human acute myeloid leukemia cells to suppress host immune surveillance.

Inna M Yasinska1, Isabel Gonçalves Silva1, Svetlana Sakhnevych1, Bernhard F Gibbs2, Ulrike Raap2, Elizaveta Fasler-Kan3,4, Vadim V Sumbayev5.   

Abstract

Acute myeloid leukaemia (AML) is a blood/bone marrow cancer originating from myeloid cell precusors capable of self-renewing. AML cells implement biochemical mechanisms which allow them not only to survive, but also to successfully escape immune surveillance. ln this work, we discuss crucial molecular mechanisms used by human AML cells in order to evade immune attack.

Entities:  

Keywords:  Acute myeloid leukaemia; Immune surveillance; Tim-3; galectin-9

Mesh：

Year:  2018        PMID： 29872115      PMCID： PMC6207652          DOI： 10.1038/s41423-018-0047-6

Source DB:  PubMed          Journal:  Cell Mol Immunol        ISSN： 1672-7681            Impact factor:   11.530


  16 in total

1.  A TIM-3/Gal-9 Autocrine Stimulatory Loop Drives Self-Renewal of Human Myeloid Leukemia Stem Cells and Leukemic Progression.

Authors:  Yoshikane Kikushige; Toshihiro Miyamoto; Junichiro Yuda; Siamak Jabbarzadeh-Tabrizi; Takahiro Shima; Shin-ichiro Takayanagi; Hiroaki Niiro; Ayano Yurino; Kohta Miyawaki; Katsuto Takenaka; Hiromi Iwasaki; Koichi Akashi
Journal:  Cell Stem Cell       Date:  2015-08-13       Impact factor: 24.633

2.  Soluble form of T cell Ig mucin 3 is an inhibitory molecule in T cell-mediated immune response.

Authors:  Hui Geng; Gui-Mei Zhang; Dong Li; Hui Zhang; Ye Yuan; Han-Gang Zhu; Han Xiao; Ling-Fei Han; Zuo-Hua Feng
Journal:  J Immunol       Date:  2006-02-01       Impact factor: 5.422

3.  Interleukin-1 beta induces the expression and production of stem cell factor by epithelial cells: crucial involvement of the PI-3K/mTOR pathway and HIF-1 transcription complex.

Authors:  Rafal W Wyszynski; Bernhard F Gibbs; Luca Varani; Daniela Iannotta; Vadim V Sumbayev
Journal:  Cell Mol Immunol       Date:  2014-11-24       Impact factor: 11.530

4.  PD-L1 co-stimulation contributes to ligand-induced T cell receptor down-modulation on CD8+ T cells.

Authors:  Katarzyna Karwacz; Christopher Bricogne; Douglas MacDonald; Frederick Arce; Clare L Bennett; Mary Collins; David Escors
Journal:  EMBO Mol Med       Date:  2011-08-10       Impact factor: 12.137

5.  TIM-3/Gal-9 interaction induces IFNγ-dependent IDO1 expression in acute myeloid leukemia blast cells.

Authors:  Valentina Folgiero; Loredana Cifaldi; Giuseppina Li Pira; Bianca Maria Goffredo; Luciana Vinti; Franco Locatelli
Journal:  J Hematol Oncol       Date:  2015-04-16       Impact factor: 17.388

6.  A Co-Inhibitory Alliance in Myeloid Leukemia: TIM-3/Galectin-9 Complex as a New Target for Checkpoint Blockade Therapy.

Authors:  M Alper Kursunel; Gunes Esendagli
Journal:  EBioMedicine       Date:  2017-08-04       Impact factor: 8.143

7.  The Tim-3-galectin-9 Secretory Pathway is Involved in the Immune Escape of Human Acute Myeloid Leukemia Cells.

Authors:  Isabel Gonçalves Silva; Inna M Yasinska; Svetlana S Sakhnevych; Walter Fiedler; Jasmin Wellbrock; Marco Bardelli; Luca Varani; Rohanah Hussain; Giuliano Siligardi; Giacomo Ceccone; Steffen M Berger; Yuri A Ushkaryov; Bernhard F Gibbs; Elizaveta Fasler-Kan; Vadim V Sumbayev
Journal:  EBioMedicine       Date:  2017-07-19       Impact factor: 8.143

8.  Expression of functional neuronal receptor latrophilin 1 in human acute myeloid leukaemia cells.

Authors:  Vadim V Sumbayev; Isabel Gonçalves Silva; Jennifer Blackburn; Bernhard F Gibbs; Inna M Yasinska; Michelle D Garrett; Alexander G Tonevitsky; Yuri A Ushkaryov
Journal:  Oncotarget       Date:  2016-07-19

9.  Apoptosis of tumor infiltrating effector TIM-3+CD8+ T cells in colon cancer.

Authors:  Chiao-Wen Kang; Avijit Dutta; Li-Yuan Chang; Jayashri Mahalingam; Yung-Chang Lin; Jy-Ming Chiang; Chen-Yu Hsu; Ching-Tai Huang; Wan-Ting Su; Yu-Yi Chu; Chun-Yen Lin
Journal:  Sci Rep       Date:  2015-10-23       Impact factor: 4.379

10.  The immune receptor Tim-3 acts as a trafficker in a Tim-3/galectin-9 autocrine loop in human myeloid leukemia cells.

Authors:  Isabel Gonçalves Silva; Laura Rüegg; Bernhard F Gibbs; Marco Bardelli; Alexander Fruehwirth; Luca Varani; Steffen M Berger; Elizaveta Fasler-Kan; Vadim V Sumbayev
Journal:  Oncoimmunology       Date:  2016-06-29       Impact factor: 8.110
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  9 in total

1.  Transcription of the Envelope Protein by 1-L Protein-RNA Recognition Code Leads to Genes/Proteins That Are Relevant to the SARS-CoV-2 Life Cycle and Pathogenesis.

Authors:  Jozef Nahalka
Journal:  Curr Issues Mol Biol       Date:  2022-02-06       Impact factor: 2.976

2.  Alliance of galectin-3 and CD74 biochemical networks as a crucial component of survival machinery operated by human acute myeloid leukaemia cells.

Authors:  Inna M Yasinska; Vadim V Sumbayev
Journal:  EBioMedicine       Date:  2019-05-30       Impact factor: 8.143

3.  Ligand-Receptor Interactions of Galectin-9 and VISTA Suppress Human T Lymphocyte Cytotoxic Activity.

Authors:  Inna M Yasinska; N Helge Meyer; Stephanie Schlichtner; Rohanah Hussain; Giuliano Siligardi; Maxwell Casely-Hayford; Walter Fiedler; Jasmin Wellbrock; Cloe Desmet; Luigi Calzolai; Luca Varani; Steffen M Berger; Ulrike Raap; Bernhard F Gibbs; Elizaveta Fasler-Kan; Vadim V Sumbayev
Journal:  Front Immunol       Date:  2020-11-20       Impact factor: 7.561

Review 4.  One Stone, Two Birds: The Roles of Tim-3 in Acute Myeloid Leukemia.

Authors:  Zhiding Wang; Jinghong Chen; Mengzhen Wang; Linlin Zhang; Li Yu
Journal:  Front Immunol       Date:  2021-04-01       Impact factor: 7.561

5.  Transforming growth factor beta type 1 (TGF-β) and hypoxia-inducible factor 1 (HIF-1) transcription complex as master regulators of the immunosuppressive protein galectin-9 expression in human cancer and embryonic cells.

Authors:  Anette Teo Hansen Selnø; Stephanie Schlichtner; Inna M Yasinska; Svetlana S Sakhnevych; Walter Fiedler; Jasmin Wellbrock; Elena Klenova; Ludmila Pavlova; Bernhard F Gibbs; Martin Degen; Isabelle Schnyder; Nijas Aliu; Steffen M Berger; Elizaveta Fasler-Kan; Vadim V Sumbayev
Journal:  Aging (Albany NY)       Date:  2020-12-08       Impact factor: 5.682

6.  Expression of the Immune Checkpoint Protein VISTA Is Differentially Regulated by the TGF-β1 - Smad3 Signaling Pathway in Rapidly Proliferating Human Cells and T Lymphocytes.

Authors:  Stephanie Schlichtner; Inna M Yasinska; Sabrina Ruggiero; Steffen M Berger; Nijas Aliu; Mateja Prunk; Janko Kos; N Helge Meyer; Bernhard F Gibbs; Elizaveta Fasler-Kan; Vadim V Sumbayev
Journal:  Front Med (Lausanne)       Date:  2022-02-10

7.  TIM-3 Expression Level on AML Blasts Correlates With Presence of Core Binding Factor Translocations Rather Than Clinical Outcomes.

Authors:  Jian Hong; Leiming Xia; Zhenqi Huang; Xiaodong Yuan; Xinglin Liang; Jifei Dai; Zhonghui Wu; Li Liang; Min Ruan; Zhangbiao Long; Xin Cheng; Xiaowen Chen; Jing Ni; Jian Ge; Qingsheng Li; Qingshu Zeng; Ruixiang Xia; Yi Wang; Mingzhen Yang
Journal:  Front Oncol       Date:  2022-04-14       Impact factor: 5.738

Review 8.  Optimizing NK Cell-Based Immunotherapy in Myeloid Leukemia: Abrogating an Immunosuppressive Microenvironment.

Authors:  Natasha Mupeta Kaweme; Fuling Zhou
Journal:  Front Immunol       Date:  2021-06-17       Impact factor: 7.561

Review 9.  Targeting Natural Killer Cells for Tumor Immunotherapy.

Authors:  Cai Zhang; Yuan Hu; Chongdeng Shi
Journal:  Front Immunol       Date:  2020-02-19       Impact factor: 7.561
  9 in total

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