Literature DB >> 29871450

Elevated daytime melatonin concentrations in autism: A pilot study.

Edward R Ritvo, Riva Ritvo, Arthur Yuwiler, Anne Brothers, B J Freeman1, Selma Plotkin2.   

Abstract

Concentrations of melatonin in overnight and first-voiding urine samples from 10 people with autism, 15 parents, 1 grandparent, 9 sibs without autism, and 10 healthy, unrelated volunteers, were measured by radioimmunoassay. Those with autism had significantly higher melatonin concentrations in the first voiding samples than controls. Groups did not differ in overnight melatonin concentrations. These preliminary results warrant replication and extension.

Entities:  

Keywords:  Melatonin; Melatonin Concentration; Pilot Study; Public Health; Urine Sample

Year:  1993        PMID： 29871450     DOI： 10.1007/BF02098862

Source DB:  PubMed          Journal:  Eur Child Adolesc Psychiatry        ISSN： 1018-8827            Impact factor:   4.785


  9 in total

1.  Adrenergic control of pineal N-acetyltransferase activity: developmental aspects.

Authors:  A Yuwiler; D C Klein; M Buda; J L Weller
Journal:  Am J Physiol       Date:  1977-09

2.  The UCLA-University of Utah epidemiologic survey of autism: prevalence.

Authors:  E R Ritvo; B J Freeman; C Pingree; A Mason-Brothers; L Jorde; W R Jenson; W M McMahon; P B Petersen; A Mo; A Ritvo
Journal:  Am J Psychiatry       Date:  1989-02       Impact factor: 18.112

3.  Electroretinograms in autism: a pilot study of b-wave amplitudes.

Authors:  E R Ritvo; D Creel; G Realmuto; A S Crandall; B J Freeman; J B Bateman; R Barr; C Pingree; M Coleman; R Purple
Journal:  Am J Psychiatry       Date:  1988-02       Impact factor: 18.112

4.  Radioimmunological determination of urinary melatonin in humans: correlation with plasma levels and typical 24-hour rhythmicity.

Authors:  U Lang; M Kornemark; M L Aubert; L Paunier; P C Sizonenko
Journal:  J Clin Endocrinol Metab       Date:  1981-09       Impact factor: 5.958

5.  Melatonin administration to dogs.

Authors:  J Sääf; L Wetterberg; M Bäckström; A Sundwall
Journal:  J Neural Transm       Date:  1980       Impact factor: 3.575

Review 6.  Melatonin in humans physiological and clinical studies.

Authors:  L Wetterberg
Journal:  J Neural Transm Suppl       Date:  1978

7.  Melatonin is a potent modulator of dopamine release in the retina.

Authors:  M L Dubocovich
Journal:  Nature       Date:  1983 Dec 22-1984 Jan 4       Impact factor: 49.962

8.  Melatonin in serum and urine in patients with idiopathic pain syndromes.

Authors:  B G Almay; L von Knorring; L Wetterberg
Journal:  Psychiatry Res       Date:  1987-11       Impact factor: 3.222

9.  Melatonin is metabolized to N-acetyl serotonin and 6-hydroxymelatonin in man.

Authors:  I M Young; R M Leone; P Francis; P Stovell; R E Silman
Journal:  J Clin Endocrinol Metab       Date:  1985-01       Impact factor: 5.958
  9 in total
  4 in total

1.  Home-cage hypoactivity in mouse genetic models of autism spectrum disorder.

Authors:  Christopher C Angelakos; Jennifer C Tudor; Sarah L Ferri; Thomas A Jongens; Ted Abel
Journal:  Neurobiol Learn Mem       Date:  2019-02-20       Impact factor: 3.109

2.  Clock Genes and Altered Sleep-Wake Rhythms: Their Role in the Development of Psychiatric Disorders.

Authors:  Annaëlle Charrier; Bertrand Olliac; Pierre Roubertoux; Sylvie Tordjman
Journal:  Int J Mol Sci       Date:  2017-04-29       Impact factor: 5.923

Review 3.  Biological Timing and Neurodevelopmental Disorders: A Role for Circadian Dysfunction in Autism Spectrum Disorders.

Authors:  Ethan Lorsung; Ramanujam Karthikeyan; Ruifeng Cao
Journal:  Front Neurosci       Date:  2021-03-12       Impact factor: 4.677

Review 4.  Melatonin and Comorbidities in Children with Autism Spectrum Disorder.

Authors:  Katia Gagnon; Roger Godbout
Journal:  Curr Dev Disord Rep       Date:  2018-08-09
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.