| Literature DB >> 29871169 |
J Wang, Y Zhao, J J Ren, L Lei, Y Xu.
Abstract
Chronic rhinosinusitis(CRS) is a highly prevalent disease, it affects approximately 2%-16% of the adult population. The prevalence of CRS is higher in patients with comorbid diseases, such as asthma, chronic obstructive pulmonary disease, and environmental allergies. The risk factors for chronic rhinosinusitis include genetic mutation, comorbid airway diseases and environmental factors.In recent years, some studies indicated that laryngopharyngeal reflux(LPR) was the potential risk factor for CRS. LPR is a kind of extraesophageal reflux.The diagnostic criteria for LPR include abnormal reflux symptom index, reflux findings score and ambulatory 24h double pHprobe monitoring. The pathogenic mechanisms involved in CRS related to LPR remains obscure. Some researches had shown that antireflux treatment could improve the syndrome of CRS patients. Further studies are need to explore the relationship between LPR and CRS. Copyright© by the Editorial Department of Journal of Clinical Otorhinolaryngology Head and Neck Surgery.Entities:
Keywords: gastroesophageal reflux; laryngopharyngeal reflux; pepsin; sinusitis
Year: 2016 PMID: 29871169 DOI: 10.13201/j.issn.1001-1781.2016.20.021
Source DB: PubMed Journal: Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi ISSN: 2096-7993