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Literature DB >> 29867233

Impact of neutralizing antibodies against AAV is a key consideration in gene transfer to nonhuman primates.

Weidong Xiao^1,2,3, Guangping Gao⁴, Chen Ling⁵, Roland W Herzog⁶, Xiao Xiao^7,8, Richard J Samulski⁹.

Abstract

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2018 PMID： 29867233 PMCID： PMC6290466 DOI： 10.1038/s41591-018-0062-2

Source DB: PubMed Journal: Nat Med ISSN： 1078-8956 Impact factor: 53.440

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13 in total

1. Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates.

Authors: Pi-Xiao Wang; Yan-Xiao Ji; Xiao-Jing Zhang; Ling-Ping Zhao; Zhen-Zhen Yan; Peng Zhang; Li-Jun Shen; Xia Yang; Jing Fang; Song Tian; Xue-Yong Zhu; Jun Gong; Xin Zhang; Qiao-Fang Wei; Yong Wang; Jing Li; Lu Wan; Qingguo Xie; Zhi-Gang She; Zhihua Wang; Zan Huang; Hongliang Li
Journal: Nat Med Date: 2017-02-20 Impact factor: 53.440

2. Impact of pre-existing immunity on gene transfer to nonhuman primate liver with adeno-associated virus 8 vectors.

Authors: Lili Wang; Roberto Calcedo; Peter Bell; Jianping Lin; Rebecca L Grant; Don L Siegel; James M Wilson
Journal: Hum Gene Ther Date: 2011-06-08 Impact factor: 5.695

3. Corrigendum: Targeting CASP8 and FADD-like apoptosis regulator ameliorates nonalcoholic steatohepatitis in mice and nonhuman primates.

4. The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis.

Authors: Yan-Xiao Ji; Zan Huang; Xia Yang; Xiaozhan Wang; Ling-Ping Zhao; Pi-Xiao Wang; Xiao-Jing Zhang; Michele Alves-Bezerra; Lin Cai; Peng Zhang; Yue-Xin Lu; Lan Bai; Mao-Mao Gao; Huan Zhao; Song Tian; Yong Wang; Zhi-Xiang Huang; Xue-Yong Zhu; Yan Zhang; Jun Gong; Zhi-Gang She; Feng Li; David E Cohen; Hongliang Li
Journal: Nat Med Date: 2018-01-01 Impact factor: 53.440

5. The deubiquitinating enzyme TNFAIP3 mediates inactivation of hepatic ASK1 and ameliorates nonalcoholic steatohepatitis.

Authors: Peng Zhang; Pi-Xiao Wang; Ling-Ping Zhao; Xin Zhang; Yan-Xiao Ji; Xiao-Jing Zhang; Chun Fang; Yue-Xin Lu; Xia Yang; Mao-Mao Gao; Yan Zhang; Song Tian; Xue-Yong Zhu; Jun Gong; Xin-Liang Ma; Feng Li; Zhihua Wang; Zan Huang; Zhi-Gang She; Hongliang Li
Journal: Nat Med Date: 2017-12-11 Impact factor: 53.440

6. Preexisting immunity and low expression in primates highlight translational challenges for liver-directed AAV8-mediated gene therapy.

Authors: Gregory D Hurlbut; Robin J Ziegler; Jennifer B Nietupski; Joseph W Foley; Lisa A Woodworth; Elizabeth Meyers; Scott D Bercury; Nilesh N Pande; David W Souza; Mark P Bree; Michael J Lukason; John Marshall; Seng H Cheng; Ronald K Scheule
Journal: Mol Ther Date: 2010-08-24 Impact factor: 11.454

7. Tmbim1 is a multivesicular body regulator that protects against non-alcoholic fatty liver disease in mice and monkeys by targeting the lysosomal degradation of Tlr4.

Authors: Guang-Nian Zhao; Peng Zhang; Jun Gong; Xiao-Jing Zhang; Pi-Xiao Wang; Miao Yin; Zhou Jiang; Li-Jun Shen; Yan-Xiao Ji; Jingjing Tong; Yutao Wang; Qiao-Fang Wei; Yong Wang; Xue-Yong Zhu; Xin Zhang; Jing Fang; Qingguo Xie; Zhi-Gang She; Zhihua Wang; Zan Huang; Hongliang Li
Journal: Nat Med Date: 2017-05-08 Impact factor: 53.440

8. Inverse zonation of hepatocyte transduction with AAV vectors between mice and non-human primates.

Authors: Peter Bell; Lili Wang; Guangping Gao; Mark E Haskins; Alice F Tarantal; Robert J McCarter; Yanqing Zhu; Hongwei Yu; James M Wilson
Journal: Mol Genet Metab Date: 2011-06-12 Impact factor: 4.797

Review 9. Overcoming the Host Immune Response to Adeno-Associated Virus Gene Delivery Vectors: The Race Between Clearance, Tolerance, Neutralization, and Escape.

Authors: Federico Mingozzi; Katherine A High
Journal: Annu Rev Virol Date: 2017-09-29 Impact factor: 10.431

10. Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy.

Authors: Guang-Ping Gao; Mauricio R Alvira; Lili Wang; Roberto Calcedo; Julie Johnston; James M Wilson
Journal: Proc Natl Acad Sci U S A Date: 2002-08-21 Impact factor: 11.205

5 in total

1. AAV Immunogenicity: A Matter of Sensitivity.

Authors: Federico Mingozzi
Journal: Mol Ther Date: 2018-09-18 Impact factor: 11.454

2. Bound Protein- and Peptide-Based Strategies for Adeno-Associated Virus Vector-Mediated Gene Therapy: Where Do We Stand Now?

Authors: Xintao Zhang; Zheng Chai; R Jude Samulski; Chengwen Li
Journal: Hum Gene Ther Date: 2020-10-22 Impact factor: 5.695

3. Immunoadsorption enables successful rAAV5-mediated repeated hepatic gene delivery in nonhuman primates.

Authors: David Salas; Karin L Kwikkers; Nerea Zabaleta; Andrea Bazo; Harald Petry; Sander J van Deventer; Gloria Gonzalez Aseguinolaza; Valerie Ferreira
Journal: Blood Adv Date: 2019-09-10

Review 4. Immunogenicity assessment of AAV-based gene therapies: An IQ consortium industry white paper.

Authors: Tong-Yuan Yang; Manuela Braun; Wibke Lembke; Fraser McBlane; John Kamerud; Stephen DeWall; Edit Tarcsa; Xiaodong Fang; Lena Hofer; Uma Kavita; Vijay V Upreti; Swati Gupta; LiNa Loo; Alison J Johnson; Rakesh Kantilal Chandode; Kay-Gunnar Stubenrauch; Maya Vinzing; Cindy Q Xia; Vibha Jawa
Journal: Mol Ther Methods Clin Dev Date: 2022-08-02 Impact factor: 5.849

Review 5. Immune Response Mechanisms against AAV Vectors in Animal Models.

Authors: Ashley T Martino; David M Markusic
Journal: Mol Ther Methods Clin Dev Date: 2019-12-25 Impact factor: 6.698

5 in total