| Literature DB >> 29866473 |
Joan A Geoghegan1, Yves F Dufrêne2.
Abstract
During colonization of biomaterials and host tissues, surface-attached bacteria are subjected to mechanical stresses, including hydrodynamic flow and cell-surface contacts. Two publications show that mechanical force activates the adhesive function of Staphylococcus aureus surface proteins, thereby providing the pathogen with a means to withstand high shear stress during colonization.Entities:
Keywords: Staphylococcus aureus; atomic-force microscopy; bacterial adhesion; catch bonds; cell-wall-anchored protein; mechanical force; shear stress
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Year: 2018 PMID： 29866473 DOI： 10.1016/j.tim.2018.05.004
Source DB: PubMed Journal: Trends Microbiol ISSN： 0966-842X Impact factor: 17.079