Qian Li1, Ying Tong1, Yong Yin2, Pinjing Cheng3, Guanzhong Gong4. 1. Radiation Physics Department of Shandong Cancer Hospital Affiliated to Shandong University, Jinan 250117, China; School of Nuclear Science and Technology, University of South China, Hengyang 421001, China. 2. Radiation Physics Department of Shandong Cancer Hospital Affiliated to Shandong University, Jinan 250117, China. 3. School of Nuclear Science and Technology, University of South China, Hengyang 421001, China. 4. Radiation Physics Department of Shandong Cancer Hospital Affiliated to Shandong University, Jinan 250117, China. Electronic address: gongguanzhong@yeah.net.
Abstract
PURPOSE: The aim was to measure the cardiac motion-induced displacements of major coronary artery bifurcations utilizing electrocardiography (ECG)-gated four-dimensional computed tomography (4D-CT) and to determine the margin of coronary artery bifurcations. METHODS: Thirty-seven female patients who underwent retrospective ECG-gated 4D-CT in inspiratory breath hold (IBH) were enrolled. The left main coronary artery bifurcation (LM), the obtuse marginal branch bifurcation (OM), the first diagonal branch bifurcation (D1), the second diagonal branch bifurcation (D2), the caudal portion of the left anterior descending branch (APX), the first right ventricular artery bifurcation (V) and the acute marginal branch bifurcation (AM) were contoured. The center of the contour of the coronary arterial bifurcations at end systole was defined as the standard, and the margin were then calculated. RESULTS: The margin in the left-right (LR), cranio-caudal (CC), and anterior-posterior (AP) coordinates were as follows: LM 3, 3, and 3 mm; D1 6, 3, and 3 mm; D2 3, 3, and 3 mm; APX 4, 4, and 4 mm; OM 4, 6, and 5 mm; V 6, 8, and 7 mm; and AM 6, 8, and 7 mm, respectively. CONCLUSION: Coronary artery bifurcations should be considered a separate organ at risk (OAR), and different margin should be provided due to the differences resulting from motion displacement. The maximum margin in the LR, CC, and AP coordinates of left coronary artery bifurcations were 6, 6, and 5 mm, and those of the right coronary artery bifurcations were 6, 8, and 7 mm, respectively.
PURPOSE: The aim was to measure the cardiac motion-induced displacements of major coronary artery bifurcations utilizing electrocardiography (ECG)-gated four-dimensional computed tomography (4D-CT) and to determine the margin of coronary artery bifurcations. METHODS: Thirty-seven female patients who underwent retrospective ECG-gated 4D-CT in inspiratory breath hold (IBH) were enrolled. The left main coronary artery bifurcation (LM), the obtuse marginal branch bifurcation (OM), the first diagonal branch bifurcation (D1), the second diagonal branch bifurcation (D2), the caudal portion of the left anterior descending branch (APX), the first right ventricular artery bifurcation (V) and the acute marginal branch bifurcation (AM) were contoured. The center of the contour of the coronary arterial bifurcations at end systole was defined as the standard, and the margin were then calculated. RESULTS: The margin in the left-right (LR), cranio-caudal (CC), and anterior-posterior (AP) coordinates were as follows: LM 3, 3, and 3 mm; D1 6, 3, and 3 mm; D2 3, 3, and 3 mm; APX 4, 4, and 4 mm; OM 4, 6, and 5 mm; V 6, 8, and 7 mm; and AM 6, 8, and 7 mm, respectively. CONCLUSION: Coronary artery bifurcations should be considered a separate organ at risk (OAR), and different margin should be provided due to the differences resulting from motion displacement. The maximum margin in the LR, CC, and AP coordinates of left coronary artery bifurcations were 6, 6, and 5 mm, and those of the right coronary artery bifurcations were 6, 8, and 7 mm, respectively.
Authors: Eric D Morris; Ahmed I Ghanem; Ming Dong; Milan V Pantelic; Eleanor M Walker; Carri K Glide-Hurst Journal: Med Phys Date: 2019-12-29 Impact factor: 4.071
Authors: Eric D Morris; Ahmed I Ghanem; Simeng Zhu; Ming Dong; Milan V Pantelic; Carri K Glide-Hurst Journal: Phys Imaging Radiat Oncol Date: 2021-04-16