| Literature DB >> 29863496 |
Abstract
Acute kidney injury comprises a heterogeneous group of conditions characterized by a sudden decrease in renal function over hours to days. Contrast-induced acute kidney injury (CI-AKI) is caused by radiographic contrast agents used in diagnostic imaging. In the current issue of the JCI, Lau et al. use a mouse model of CI-AKI to study the role of resident and infiltrating phagocytes, recruited leukocytes, and tubular cells in the immune surveillance response to contrast agents. This study has the potential to provide innovative therapies for human CI-AKI.Entities:
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Year: 2018 PMID: 29863496 PMCID: PMC6025966 DOI: 10.1172/JCI121741
Source DB: PubMed Journal: J Clin Invest ISSN: 0021-9738 Impact factor: 14.808