Hamza Azam1, Sara Shahrestani1, Kevin Phan1,2. 1. Faculty of Medicine, Westmead Clinical School, University of Sydney, Sydney, Australia. 2. Liverpool Hospital, Liverpool, Sydney, Australia.
Abstract
BACKGROUND: There have been increasing reports of increased risk of alcohol use disorder (AUD) in the post bariatric surgery patient. The aim of this systematic review and meta-analysis is to observe the rate of AUD in the postoperative period following bariatric surgery for weight management. METHODS: Electronic searches were performed using six databases from their dates of inception to January 2017. Studies observing the trend in AUD post bariatric surgery were identified. Data for relevant endpoint was extracted and analysed. RESULTS: Ten studies were identified for inclusion of analyses. One year post operatively pooled odds were 1.004 [95% confidence interval (CI), 0.921-1.094; P=0.935], with no significant difference found in the proportion of patients with AUD at 1 year vs. pre-surgery. Two years post operatively pooled odds were 0.981 (95% CI, 0.843-1.142; P=0.806), with no significant difference found in the proportion of patients with AUD at 2 years vs. pre-surgery. Three years post operatively pooled odds were 1.825 (95% CI, 1.53-2.178; P<0.001) with a significant increase in AUD particularly with gastric bypass surgery. CONCLUSIONS: In conclusion, prevalence of AUD increases in patients undergoing gastric bypass surgery but not gastric banding. The risk of AUD was found to not be significantly increased in the first 2 years postoperatively but increasing after this period.
BACKGROUND: There have been increasing reports of increased risk of alcohol use disorder (AUD) in the post bariatric surgery patient. The aim of this systematic review and meta-analysis is to observe the rate of AUD in the postoperative period following bariatric surgery for weight management. METHODS: Electronic searches were performed using six databases from their dates of inception to January 2017. Studies observing the trend in AUD post bariatric surgery were identified. Data for relevant endpoint was extracted and analysed. RESULTS: Ten studies were identified for inclusion of analyses. One year post operatively pooled odds were 1.004 [95% confidence interval (CI), 0.921-1.094; P=0.935], with no significant difference found in the proportion of patients with AUD at 1 year vs. pre-surgery. Two years post operatively pooled odds were 0.981 (95% CI, 0.843-1.142; P=0.806), with no significant difference found in the proportion of patients with AUD at 2 years vs. pre-surgery. Three years post operatively pooled odds were 1.825 (95% CI, 1.53-2.178; P<0.001) with a significant increase in AUD particularly with gastric bypass surgery. CONCLUSIONS: In conclusion, prevalence of AUD increases in patients undergoing gastric bypass surgery but not gastric banding. The risk of AUD was found to not be significantly increased in the first 2 years postoperatively but increasing after this period.
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