Literature DB >> 29862164

Single-Cell Transcriptome Analysis of Neural Stem Cells.

Ying Li1, Jeremy Anderson1, Kelvin Y Kwan2, Li Cai1.   

Abstract

Neural stem cells (NSCs) in the adult central nervous system play essential roles in both normal homeostasis and repair of damaged tissue after injury. The study of adult NSCs is hampered by the heterogeneous NSC population. In this review, we describe recent progresses in using single-cell RNA-sequencing (scRNA-seq) technique for the investigation of NSCs. The first part of this review focuses on the scRNA-seq techniques and bioinformatic analysis. The second part emphasizes the applications of scRNA-seq analysis in NSC research. Finally, we discuss the challenges and future directions of scRNA-seq technique for both basic research and regenerative medicine.

Entities:  

Keywords:  Bioinformatics; Homeostasis; Injury and diseases; Neural stem cells; Single-cell sequencing; Transcriptome

Year:  2017        PMID： 29862164      PMCID： PMC5984046          DOI： 10.1007/s40495-017-0084-3

Source DB:  PubMed          Journal:  Curr Pharmacol Rep        ISSN： 2198-641X


  56 in total

Review 1.  Design and Analysis of Single-Cell Sequencing Experiments.

Authors:  Dominic Grün; Alexander van Oudenaarden
Journal:  Cell       Date:  2015-11-05       Impact factor: 41.582

2.  Laser-capture microdissection.

Authors:  Virginia Espina; Julia D Wulfkuhle; Valerie S Calvert; Amy VanMeter; Weidong Zhou; George Coukos; David H Geho; Emanuel F Petricoin; Lance A Liotta
Journal:  Nat Protoc       Date:  2006       Impact factor: 13.491

3.  Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development.

Authors:  Sean C Bendall; Kara L Davis; El-Ad David Amir; Michelle D Tadmor; Erin F Simonds; Tiffany J Chen; Daniel K Shenfeld; Garry P Nolan; Dana Pe'er
Journal:  Cell       Date:  2014-04-24       Impact factor: 41.582

Review 4.  Computational methods for transcriptome annotation and quantification using RNA-seq.

Authors:  Manuel Garber; Manfred G Grabherr; Mitchell Guttman; Cole Trapnell
Journal:  Nat Methods       Date:  2011-05-27       Impact factor: 28.547

5.  Neurogenic Radial Glia-like Cells in Meninges Migrate and Differentiate into Functionally Integrated Neurons in the Neonatal Cortex.

Authors:  Francesco Bifari; Ilaria Decimo; Annachiara Pino; Enric Llorens-Bobadilla; Sheng Zhao; Christian Lange; Gabriella Panuccio; Bram Boeckx; Bernard Thienpont; Stefan Vinckier; Sabine Wyns; Ann Bouché; Diether Lambrechts; Michele Giugliano; Mieke Dewerchin; Ana Martin-Villalba; Peter Carmeliet
Journal:  Cell Stem Cell       Date:  2016-11-23       Impact factor: 24.633

Review 6.  Rapid Spread of Zika Virus in The Americas--Implications for Public Health Preparedness for Mass Gatherings at the 2016 Brazil Olympic Games.

Authors:  Eskild Petersen; Mary E Wilson; Sok Touch; Brian McCloskey; Peter Mwaba; Matthew Bates; Osman Dar; Frank Mattes; Mike Kidd; Giuseppe Ippolito; Esam I Azhar; Alimuddin Zumla
Journal:  Int J Infect Dis       Date:  2016-02-04       Impact factor: 3.623

7.  Tumour evolution inferred by single-cell sequencing.

Authors:  Nicholas Navin; Jude Kendall; Jennifer Troge; Peter Andrews; Linda Rodgers; Jeanne McIndoo; Kerry Cook; Asya Stepansky; Dan Levy; Diane Esposito; Lakshmi Muthuswamy; Alex Krasnitz; W Richard McCombie; James Hicks; Michael Wigler
Journal:  Nature       Date:  2011-03-13       Impact factor: 49.962

8.  Expression Analysis Highlights AXL as a Candidate Zika Virus Entry Receptor in Neural Stem Cells.

Authors:  Tomasz J Nowakowski; Alex A Pollen; Elizabeth Di Lullo; Carmen Sandoval-Espinosa; Marina Bershteyn; Arnold R Kriegstein
Journal:  Cell Stem Cell       Date:  2016-03-30       Impact factor: 24.633

9.  Oscope identifies oscillatory genes in unsynchronized single-cell RNA-seq experiments.

Authors:  Ning Leng; Li-Fang Chu; Chris Barry; Yuan Li; Jeea Choi; Xiaomao Li; Peng Jiang; Ron M Stewart; James A Thomson; Christina Kendziorski
Journal:  Nat Methods       Date:  2015-08-24       Impact factor: 28.547

10.  CellTree: an R/bioconductor package to infer the hierarchical structure of cell populations from single-cell RNA-seq data.

Authors:  David A duVerle; Sohiya Yotsukura; Seitaro Nomura; Hiroyuki Aburatani; Koji Tsuda
Journal:  BMC Bioinformatics       Date:  2016-09-13       Impact factor: 3.169
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  1 in total

1.  Gliogenic Potential of Single Pallial Radial Glial Cells in Lower Cortical Layers.

Authors:  Ana Cristina Ojalvo-Sanz; Laura López-Mascaraque
Journal:  Cells       Date:  2021-11-19       Impact factor: 6.600
  1 in total

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