| Literature DB >> 2986069 |
D F Miller, J W Bay, R J Lederman, J D Purvis, L R Rogers, R L Tomsak.
Abstract
Eleven patients treated with intracarotid BCNU, cisplatinum, or BCNU and cisplatinum in combination for recurrent malignant gliomas were followed with serial ophthalmologic examinations for 2 to 11 months. Eight patients developed significant visual loss ipsilateral to the side of infusion. Secondary glaucoma and internal ophthalmoplegia were new complications observed after BCNU treatment. An unusual pigmentary retinopathy, previously unreported, was seen in patients treated with cisplatinum. One patient also developed a cavernous sinus syndrome after the intracarotid administration of cisplatinum.Entities:
Mesh:
Substances:
Year: 1985 PMID: 2986069 DOI: 10.1016/s0161-6420(85)34036-8
Source DB: PubMed Journal: Ophthalmology ISSN: 0161-6420 Impact factor: 12.079