| Literature DB >> 29858812 |
Abstract
The established standards for HLA genotyping rely on targeted DNA sequencing techniques. However, the increasing abundance of short-read sequencing data has prompted a demand for computational tools capable of HLA typing from general purpose sequencing data as well. OptiType is a software that performs HLA typing from short-read DNA and RNA sequencing data, and this chapter guides the user through its installation and usage.Keywords: Bioinformatics; HLA class I typing; In silico; Mapping; OptiType; RNA-Seq; Whole-exome Seq
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Year: 2018 PMID： 29858812 DOI： 10.1007/978-1-4939-8546-3_15
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745