Literature DB >> 29858801

Allele Frequency Net Database.

Faviel F Gonzalez-Galarza1, Antony McCabe2, Eduardo J Melo Dos Santos3, Louise Takeshita2, Gurpreet Ghattaoraya2, Andrew R Jones2, Derek Middleton4,5.   

Abstract

The allele frequency net database (AFND, http://www.allelefrequencies.net ) is an online web-based repository that contains information on the frequencies of immune-related genes and their corresponding alleles in worldwide human populations. At present, the system contains data from 1505 populations in more than ten million individuals on the frequency of genes from different polymorphic regions including data for the human leukocyte antigens (HLA) system. This resource has been widely used in a variety of contexts such as histocompatibility, immunology, epidemiology, pharmacogenetics, and population genetics, among many others. In this chapter, we present some of the more commonly used searching mechanisms and some of the most recent developments included in AFND.

Entities:  

Keywords:  Frequencies; HLA; Immunogenetics; Polymorphisms; Population genetics

Mesh:

Substances:

Year:  2018        PMID: 29858801     DOI: 10.1007/978-1-4939-8546-3_4

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  7 in total

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Authors:  Ellen K Wagner; Ahlam N Qerqez; Christopher A Stevens; Annalee W Nguyen; George Delidakis; Jennifer A Maynard
Journal:  J Biol Chem       Date:  2019-02-22       Impact factor: 5.157

2.  Diversity of KIR, HLA Class I, and Their Interactions in Seven Populations of Sub-Saharan Africans.

Authors:  Neda Nemat-Gorgani; Lisbeth A Guethlein; Brenna M Henn; Steven J Norberg; Jacques Chiaroni; Martin Sikora; Lluis Quintana-Murci; Joanna L Mountain; Paul J Norman; Peter Parham
Journal:  J Immunol       Date:  2019-03-27       Impact factor: 5.422

3.  HLA class II variants defined by next generation sequencing are associated with sarcoidosis in Korean patients.

Authors:  Kateřina Sikorová; Su-Jin Moon; Hee-Young Yoon; Adam Strnad; Jin Woo Song; Martin Petrek
Journal:  Sci Rep       Date:  2022-06-03       Impact factor: 4.996

4.  INeo-Epp: A Novel T-Cell HLA Class-I Immunogenicity or Neoantigenic Epitope Prediction Method Based on Sequence-Related Amino Acid Features.

Authors:  Guangzhi Wang; Huihui Wan; Xingxing Jian; Yuyu Li; Jian Ouyang; Xiaoxiu Tan; Yong Zhao; Yong Lin; Lu Xie
Journal:  Biomed Res Int       Date:  2020-06-15       Impact factor: 3.411

5.  Characterization of Antigenic MHC-Class-I-Restricted T Cell Epitopes in the Glycoprotein of Ebolavirus.

Authors:  Jonathan Powlson; Daniel Wright; Antra Zeltina; Mark Giza; Morten Nielsen; Tommy Rampling; Navin Venkatrakaman; Thomas A Bowden; Adrian V S Hill; Katie J Ewer
Journal:  Cell Rep       Date:  2019-11-26       Impact factor: 9.423

6.  Initial whole-genome sequencing and analysis of the host genetic contribution to COVID-19 severity and susceptibility.

Authors:  Fang Wang; Shujia Huang; Rongsui Gao; Yuwen Zhou; Changxiang Lai; Zhichao Li; Wenjie Xian; Xiaobo Qian; Zhiyu Li; Yushan Huang; Qiyuan Tang; Panhong Liu; Ruikun Chen; Rong Liu; Xuan Li; Xin Tong; Xuan Zhou; Yong Bai; Gang Duan; Tao Zhang; Xun Xu; Jian Wang; Huanming Yang; Siyang Liu; Qing He; Xin Jin; Lei Liu
Journal:  Cell Discov       Date:  2020-11-10       Impact factor: 10.849

7.  HLA-A, -B, -C, -DRB1, -DQB1, and -DPB1 Allele and Haplotype Frequencies of 28,927 Saudi Stem Cell Donors Typed by Next-Generation Sequencing.

Authors:  Dunia Jawdat; F Aytül Uyar; Ahmed Alaskar; Carlheinz R Müller; Ali Hajeer
Journal:  Front Immunol       Date:  2020-10-22       Impact factor: 7.561

  7 in total

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