Dilsad Mungan1, Omur Aydin2, Bassam Mahboub3, Mohammad Albader4, Hesham Tarraf5, Adam Doble6, Aaicha Lahlou7, Luqman Tariq8, Fayaz Aziz9, Abdelkader El Hasnaoui10. 1. Department of Chest Diseases, Division of Allergy and Immunology, Ankara University, School of Medicine, Turkey. Electronic address: dilsadmungan@gmail.com. 2. Department of Chest Diseases, Division of Allergy and Immunology, Ankara University, School of Medicine, Turkey. Electronic address: mdomuraydin@gmail.com. 3. College of Medicine, University of Sharjah, Sharjah, UAE and Department of Pulmonary Medicine, Rashid Hospital, Dubai, United Arab Emirates. Electronic address: drbassam_mahboub@yahoo.com. 4. Chest Medicine Department, Zain Hospital, Kuwait. Electronic address: Albader1219@yahoo.com. 5. The Medical School, Cairo University, Cairo, Egypt. Electronic address: tarraf_hisham@hotmail.com. 6. Foxymed, Paris, France. Electronic address: adam@foxymed.com. 7. MS Health, Rabat, Morocco. Electronic address: alahlou@mshealth.ma. 8. GlaxoSmithKline, Dubai, United Arab Emirates. Electronic address: luqman.l.tariq@gsk.com. 9. GlaxoSmithKline, Dubai, United Arab Emirates. Electronic address: fayaz.a.aziz@gsk.com. 10. GlaxoSmithKline, Dubai, United Arab Emirates. Electronic address: abdelkader.a.el-hasnaoui@gsk.com.
Abstract
BACKGROUND: Asthma affects millions worldwide resulting in a significant disease burden. However, data on asthma burden from the Middle East is limited. This analysis describes the asthma burden in Egypt, Turkey and a Gulf cluster (Kuwait, Saudi Arabia and United Arab Emirates) as part of the SNAPSHOT program. METHODS: SNAPSHOT was an observational, cross-sectional program carried out by telephone in a random sample of the adult general population of the five above mentioned countries. Quotas were defined per country demographics. Subjects were considered to have asthma if they fulfilled the screening criteria, based on the global Asthma Insights and Reality studies. Data collected included demographics, physician consultations, and asthma control (measured by the Asthma Control Test; ACT). Quality of life was assessed using the EuroQol Five-Dimension questionnaire (EQ-5D); and limitations to daily activities using the modified Sheehan Disability Scale (SDS). RESULTS: 939 subjects answered questions related to asthma burden. Overall, 367 (44.2%) reported uncontrolled asthma (ACT≤19), and reported significantly lower EQ-5D-3L utility values (0.6 ± 0.4) and EQ-VAS scores (60.7 ± 24.2) compared to controlled subjects (0.8 ± 0.3 and 75.3 ± 19.8 respectively) (p < 0.0001). A significantly higher proportion with uncontrolled asthma also reported experiencing impact on activities of daily living compared to subjects with controlled asthma (p < 0.0001). Overall, 355 (37.8%) asthma subjects were followed by a physician. However, most visits were unscheduled (695;78.0%). CONCLUSION: Uncontrolled asthma imposes a significant burden in these Middle Eastern countries resulting in increased frequency of healthcare use, lower quality of life, and a higher impact on daily life compared to controlled asthma.
BACKGROUND:Asthma affects millions worldwide resulting in a significant disease burden. However, data on asthma burden from the Middle East is limited. This analysis describes the asthma burden in Egypt, Turkey and a Gulf cluster (Kuwait, Saudi Arabia and United Arab Emirates) as part of the SNAPSHOT program. METHODS: SNAPSHOT was an observational, cross-sectional program carried out by telephone in a random sample of the adult general population of the five above mentioned countries. Quotas were defined per country demographics. Subjects were considered to have asthma if they fulfilled the screening criteria, based on the global Asthma Insights and Reality studies. Data collected included demographics, physician consultations, and asthma control (measured by the Asthma Control Test; ACT). Quality of life was assessed using the EuroQol Five-Dimension questionnaire (EQ-5D); and limitations to daily activities using the modified Sheehan Disability Scale (SDS). RESULTS: 939 subjects answered questions related to asthma burden. Overall, 367 (44.2%) reported uncontrolled asthma (ACT≤19), and reported significantly lower EQ-5D-3L utility values (0.6 ± 0.4) and EQ-VAS scores (60.7 ± 24.2) compared to controlled subjects (0.8 ± 0.3 and 75.3 ± 19.8 respectively) (p < 0.0001). A significantly higher proportion with uncontrolled asthma also reported experiencing impact on activities of daily living compared to subjects with controlled asthma (p < 0.0001). Overall, 355 (37.8%) asthma subjects were followed by a physician. However, most visits were unscheduled (695;78.0%). CONCLUSION: Uncontrolled asthma imposes a significant burden in these Middle Eastern countries resulting in increased frequency of healthcare use, lower quality of life, and a higher impact on daily life compared to controlled asthma.
Authors: Khulood Al Mazrouei; Asma Ibrahim Almannaei; Faiza Medeni Nur; Nagham Bachnak; Ashraf Alzaabi Journal: Clinicoecon Outcomes Res Date: 2021-12-29
Authors: Shaker A Alomary; Ahmed J Al Madani; Wael A Althagafi; Izzeldin F Adam; Omneya E Elsherif; Aljoharah A Al-Abdullaah; Hamdan Al-Jahdali; Hani A Jokhdar; Saeed H Alqahtani; Mahmoud A Nahhas; Rasha A Alfawaz Journal: World Allergy Organ J Date: 2022-01-10 Impact factor: 4.084