Literature DB >> 29857929

Postapproval Community Hospital Experience in the United States with Left Atrial Appendage Closure Device (Watchman).

Koroush Khalighi1, Munish Sharma2, Rohit Masih3, Vadim Levin4.   

Abstract

BACKGROUND: To review the procedural safety and postimplantation complications of Watchman device implanted at 2 community hospitals for primary prevention of systemic embolization in patients with nonvalvular atrial fibrillation (NVAF) who were not candidates for long-term oral anticoagulation (OAC).
METHODS: This was a retrospective case series of 48 patients carried out in 2 community hospitals in the United States. Patients with NVAF who had a CHADS2 higher than 2 or CHADS2VASc2 (congestive heart failure, hypertension, age ≥75 years, diabetes mellitus, prior stroke or transient ischemic attack [TIA] or thromboembolism, vascular disease, age 65-74 years, and female gender) score of 3 or higher and were not candidates for long-term OAC. These patients were selected for implantation of Watchman device. They were followed up at 45 days, 6 months, 9 months, and 12 months after implantation of Watchman device to assess for complications involving the device and to determine if anticoagulation could be discontinued at the 45 days follow-up. They were monitored for any systemic thromboembolism while off anticoagulation.
RESULTS: The success rate of device implantation was 98% (48 of 49). Only a single patient could not get Watchman implantation because of unfavorable left atrial appendage anatomy. Access-related and device implantation-related complications were zero (0%). At 45 days follow-up and end of follow-up duration, the rate of thrombus formation on the Watchman device was 4% (2 of 48). One patient had TIA after warfarin discontinuation.
CONCLUSION: With improved procedural technique and well-trained operators, Watchman implantation is feasible in a community hospital also.
Copyright © 2018 National Stroke Association. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Nonvalvular atrial fibrillation; Watchman device; community hospital; left atrial appendage closure device; stroke prevention

Mesh:

Year:  2018        PMID: 29857929     DOI: 10.1016/j.jstrokecerebrovasdis.2018.05.016

Source DB:  PubMed          Journal:  J Stroke Cerebrovasc Dis        ISSN: 1052-3057            Impact factor:   2.136


  4 in total

1.  Watchman outcomes comparing post-implantation anticoagulation with warfarin versus direct oral anticoagulants.

Authors:  Ethan Fry; Harini Bollempali; Keith Suarez; Javier Banchs; Jeffrey Michel
Journal:  J Interv Card Electrophysiol       Date:  2020-06-05       Impact factor: 1.900

2.  Short-Term Antiplatelet Versus Anticoagulant Therapy After Left Atrial Appendage Occlusion: A Systematic Review and Meta-Analysis.

Authors:  Mohammed Osman; Tatiana Busu; Khansa Osman; Safi U Khan; Matthew Daniels; David R Holmes; Mohamad Alkhouli
Journal:  JACC Clin Electrophysiol       Date:  2020-01-29

Review 3.  Clinical follow-up of left atrial appendage occlusion in patients with atrial fibrillation ineligible of oral anticoagulation treatment-a systematic review and meta-analysis.

Authors:  Frida Labori; Carl Bonander; Josefine Persson; Mikael Svensson
Journal:  J Interv Card Electrophysiol       Date:  2021-02-13       Impact factor: 1.900

4.  Meta-analysis of postoperative antithrombotic therapy after left atrial appendage occlusion.

Authors:  Shu-Yue Li; Juan Wang; Xiang Hui; Huai-Jun Zhu; Bao-Yan Wang; Hang Xu
Journal:  J Int Med Res       Date:  2020-11       Impact factor: 1.671

  4 in total

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