| Literature DB >> 29856949 |
Abstract
Chimeric antigen receptor (CAR) T cells offer a promising treatment option for advanced cancers resistant to standard therapy. Here, Cho et al. report a split-CAR design that enables the engineering of multi-feature CAR-T cells, aiming to address current challenges limiting the safety and efficacy of CAR-T cells for cancer treatment.Entities:
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Year: 2018 PMID： 29856949 DOI： 10.1016/j.cell.2018.05.030
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582