Literature DB >> 2985519

Adduct formation is involved in radiosensitization, mediated by cytochrome c, of phi X174 DNA by misonidazole.

M V Lafleur, E J Plijmackers-Westmijze, A C Loman, H Loman.   

Abstract

Radiosensitization by misonidazole of biologically active phi X174 DNA, mediated by cytochrome c, is most probably at least partly due to formation of an adduct between sensitizer and DNA, which can be removed from the DNA by a mild alkaline treatment thereby restoring the activity of the DNA.

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Year:  1985        PMID: 2985519

Source DB:  PubMed          Journal:  Int J Radiat Biol Relat Stud Phys Chem Med        ISSN: 0020-7616


  2 in total

Review 1.  Radiation damage to phi X174 DNA and biological effects.

Authors:  M V Lafleur; H Loman
Journal:  Radiat Environ Biophys       Date:  1986       Impact factor: 1.925

2.  Cellular mechanism of action of 2-nitroimidazoles as hypoxia-selective therapeutic agents.

Authors:  Faisal Bin Rashed; Diana Diaz-Dussan; Fatemeh Mashayekhi; Dawn Macdonald; Patrick Nicholas Nation; Xiao-Hong Yang; Sargun Sokhi; Alexandru Cezar Stoica; Hassan El-Saidi; Carolynne Ricardo; Ravin Narain; Ismail Hassan Ismail; Leonard Irving Wiebe; Piyush Kumar; Michael Weinfeld
Journal:  Redox Biol       Date:  2022-03-21       Impact factor: 10.787

  2 in total

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