Literature DB >> 29854108

Improving the 'Fitness for Purpose' of Common Data Models through Realism Based Ontology.

Jonathan C Blaisure1,2, Werner M Ceusters1,2.   

Abstract

Common data models are designed and built based on requirements that are aimed towards fitness for purpose. But when common data models are used as lenses through which reality is observed from the perspective according to which they are built, then they exhibit restrictions that distort such view. Realism-based ontology design, when done properly, does not have these limitations as its fitness for purpose is only determined by the degree to which reality is represented the way it is. Therefore, we can use the principles that realism-based ontologies adhere to, not only to design application ontologies serving some specific purpose, but also to assess whether and where common data models fall short in their representational adequacy and how they can be corrected. If a realism based ontological perspective on the portion of reality the some common data model is trying to represent is compared with the perspective of the common data model itself, it is possible to determine how the latter deviates from the former and to suggest solutions to correct the misrepresentations found. Applying this method to the common data model of the Observational Medical Outcomes Partnership, revealed two major categories of errors: one where relationships are restricted based on the constraints of the data model, and one where the representation of reality is oversimplified.

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Year:  2018        PMID: 29854108      PMCID: PMC5977618     

Source DB:  PubMed          Journal:  AMIA Annu Symp Proc        ISSN: 1559-4076


  15 in total

1.  Ontological realism: A methodology for coordinated evolution of scientific ontologies.

Authors:  Barry Smith; Werner Ceusters
Journal:  Appl Ontol       Date:  2010-11-15       Impact factor: 1.115

2.  A translational engine at the national scale: informatics for integrating biology and the bedside.

Authors:  Isaac S Kohane; Susanne E Churchill; Shawn N Murphy
Journal:  J Am Med Inform Assoc       Date:  2011-11-10       Impact factor: 4.497

3.  Global clinical data interchange standards are here!

Authors:  Tammy Souza; Rebecca Kush; Julie P Evans
Journal:  Drug Discov Today       Date:  2007-01-08       Impact factor: 7.851

4.  HL7 RIM: an incoherent standard.

Authors:  Barry Smith; Werner Ceusters
Journal:  Stud Health Technol Inform       Date:  2006

5.  Identifying appropriate reference data models for comparative effectiveness research (CER) studies based on data from clinical information systems.

Authors:  Omolola I Ogunyemi; Daniella Meeker; Hyeon-Eui Kim; Naveen Ashish; Seena Farzaneh; Aziz Boxwala
Journal:  Med Care       Date:  2013-08       Impact factor: 2.983

6.  The Patient-Centered Outcomes Research Network: a national infrastructure for comparative effectiveness research.

Authors:  Robert M Califf
Journal:  N C Med J       Date:  2014 May-Jun

7.  Evaluating common data models for use with a longitudinal community registry.

Authors:  Maryam Garza; Guilherme Del Fiol; Jessica Tenenbaum; Anita Walden; Meredith Nahm Zozus
Journal:  J Biomed Inform       Date:  2016-10-29       Impact factor: 6.317

8.  Creating a Common Data Model for Comparative Effectiveness with the Observational Medical Outcomes Partnership.

Authors:  F FitzHenry; F S Resnic; S L Robbins; J Denton; L Nookala; D Meeker; L Ohno-Machado; M E Matheny
Journal:  Appl Clin Inform       Date:  2015-08-26       Impact factor: 2.342

9.  Toward an ontological treatment of disease and diagnosis.

Authors:  Richard H Scheuermann; Werner Ceusters; Barry Smith
Journal:  Summit Transl Bioinform       Date:  2009-03-01

10.  The HMO Research Network Virtual Data Warehouse: A Public Data Model to Support Collaboration.

Authors:  Tyler R Ross; Daniel Ng; Jeffrey S Brown; Roy Pardee; Mark C Hornbrook; Gene Hart; John F Steiner
Journal:  EGEMS (Wash DC)       Date:  2014-03-24
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  1 in total

1.  Enhancing the Representational Power of i2b2 through Referent Tracking.

Authors:  Jonathan C Blaisure; Werner M Ceusters
Journal:  AMIA Annu Symp Proc       Date:  2018-12-05
  1 in total

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