Literature DB >> 2985180

Suprachiasmatic nucleus ablation abolishes circadian rhythms in rat brain neurotransmitter receptors.

M S Kafka, P J Marangos, R Y Moore.   

Abstract

The effect of suprachiasmatic nucleus (SCN) ablation on rhythms in brain neurotransmitter receptors was studied. In control animals, the rhythms in the number of alpha-adrenergic and benzodiazepine receptors were circadian, whereas the rhythms in beta-adrenergic and acetylcholine receptors were ultradian. SCN ablation resulted in loss of circadian, but not ultradian, rhythms, without change in the 24-h mean numbers. SCN ablation appears to cause a selective loss of circadian function in the regulation of brain receptors.

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Year:  1985        PMID: 2985180     DOI: 10.1016/0006-8993(85)91533-1

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  3 in total

Review 1.  The rhythmic GABAergic system.

Authors:  D P Cardinali; D A Golombek
Journal:  Neurochem Res       Date:  1998-05       Impact factor: 3.996

2.  The preoptic-suprachiasmatic nuclei though morphologically heterogeneous are equally affected by streptozotocin diabetes.

Authors:  G Bestetti; R Hofer; G L Rossi
Journal:  Exp Brain Res       Date:  1987       Impact factor: 1.972

3.  ERK/MAPK is essential for endogenous neuroprotection in SCN2.2 cells.

Authors:  Sumedha W Karmarkar; Kathleen M Bottum; Stacey L Krager; Shelley A Tischkau
Journal:  PLoS One       Date:  2011-08-17       Impact factor: 3.240

  3 in total

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