| Literature DB >> 2984979 |
N Kalsheker, D Chiswell, A Markham, A Imam, S Wallis, R Williamson, S E Humphries.
Abstract
We describe the basic principles of recombinant DNA technology and how this methodology has been used to isolate and characterise cloned genes coding for alpha 1-antitrypsin. We show how these probes can be used for diagnosis and to study molecular variants of alpha 1-antitrypsin which may predispose individuals to develop lung disease.Entities:
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Year: 1985 PMID： 2984979 DOI： 10.1177/000456328502200102
Source DB: PubMed Journal: Ann Clin Biochem ISSN： 0004-5632 Impact factor: 2.057