[Cartilage/chondrocyte research and osteoarthritis. The role of microRNAs and extracellular vesicles in osteoarthritis pathogenesis.]

Extracellular vesicles(EV)have been emerged as carrier for the exchange of microRNAs and bioactive factors within cartilage and between joint tissues to promote joint homeostasis and osteoarthritis(OA)pathogenesis. The purpose of this review is to describe how microRNAs and EV regulate functions of chondrocytes in OA pathogenesis.