Literature DB >> 29848090

Clinical profile, management and outcomes in a cohort of elderly and highly comorbid patients with nonvalvular atrial fibrillation treated with rivaroxaban in routine practice.

David Brun Guinda1, Óscar Callen García2, Jorge Ondiviela Pérez1, María Gracia Aznarez1, Pilar Artero Bello1, Elena Rivero Fernandez1, Adolfo Marquina Barcos1, Maite Villarroel Salcedo1.   

Abstract

AIM: To analyze clinical profile and management of patients with nonvalvular atrial fibrillation treated with rivaroxaban in clinical practice according to age and to ascertain rates of thromboembolic and bleeding events during rivaroxaban therapy.
METHODS: Retrospective study of nonvalvular atrial fibrillation patients that started rivaroxaban therapy between May 2013 and February 2017 in the cardiology department of two hospitals from Huesca, Spain.
RESULTS: A total of 137 patients (mean age 78.2 ± 8.9 years; CHA2DS2-VASc 3.5 ± 1.3; HAS-BLED 1.6 ± 0.7) were included. Comorbidity was common. After a mean duration of treatment of 30.5 ± 17.2 months, no strokes were reported. Rates of transient ischemic attack, major bleeding and intracranial bleeding were low.
CONCLUSION: In this cohort of elderly and highly comorbid patients treated with rivaroxaban, rates of thromboembolic and bleeding events were low.

Entities:  

Keywords:  atrial fibrillation; cardiology; clinical practice; rivaroxaban; stroke

Mesh:

Substances:

Year:  2018        PMID: 29848090     DOI: 10.2217/fca-2018-0025

Source DB:  PubMed          Journal:  Future Cardiol        ISSN: 1479-6678


  3 in total

Review 1.  Impact of direct oral anticoagulant off-label doses on clinical outcomes of atrial fibrillation patients: A systematic review.

Authors:  Joana Santos; Natália António; Marília Rocha; Ana Fortuna
Journal:  Br J Clin Pharmacol       Date:  2020-02-05       Impact factor: 4.335

2.  Outcomes and predictive value of the 2MACE score in patients with atrial fibrillation treated with rivaroxaban in a prospective, multicenter observational study: The EMIR study.

Authors:  Marcelo Sanmartín Fernández; Manuel Anguita Sánchez; Fernando Arribas; Gonzalo Barón-Esquivias; Vivencio Barrios; Juan Cosin-Sales; María Asunción Esteve-Pastor; Roman Freixa-Pamias; Iñaki Lekuona; Alejandro I Pérez-Cabeza; Isabel Ureña; José Manuel Vázquez Rodríguez; Carles Rafols Priu; Francisco Marin
Journal:  Cardiol J       Date:  2022-05-27       Impact factor: 3.487

3.  Clinical profile and management of rivaroxaban in patients with atrial fibrillation in routine practice in Spain: data from six nationwide studies.

Authors:  Manuel Anguita; Mariano de la Figuera; Alejandro I Pérez Cabeza; Carmen Suarez Fernández
Journal:  Drugs Context       Date:  2019-10-09
  3 in total

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