Literature DB >> 2984006

Autoradiographic localisation of opiate receptors in rat small intestine.

M R Dashwood, E S Debnam, J Bagnall, C S Thompson.   

Abstract

[3H]Naloxone and [3H]dihydromorphine are selective ligands for opiate receptors. Using an in vitro autoradiographic technique, binding of these ligands has been demonstrated to the villi and crypts in rat small intestine. These results indicate the presence of opiate receptor sites in the small intestine which suggests further a role for endogenous opiates in the transport functions of intestinal mucosa.

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Year:  1985        PMID: 2984006     DOI: 10.1016/0014-2999(85)90068-8

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN: 0014-2999            Impact factor:   4.432


  3 in total

1.  Meal-stimulated release of methionine-enkephalin into the canine jejunal lumen.

Authors:  S R Money; A Petroianu; A R Gintzler; B M Jaffe
Journal:  J Clin Invest       Date:  1988-03       Impact factor: 14.808

2.  Difenoxin and loperamide: studies on possible mechanisms of intestinal antisecretory action.

Authors:  A De Luca; I M Coupar
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1993-02       Impact factor: 3.000

3.  Regulation of L-valine absorption by opioids interacting with mu-receptors in rabbit ileum.

Authors:  G Meyer; G Bottà; G Fedele; D Cremaschi
Journal:  Experientia       Date:  1995-11-15
  3 in total

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