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Literature DB >> 298352

Chronic Parkinsonism secondary to intravenous injection of meperidine analogues.

G C Davis, A C Williams, S P Markey, M H Ebert, E D Caine, C M Reichert, I J Kopin.

Abstract

Abuse of 4-propyloxy-4-phenyl-N-methylpiperidine, a meperidine congener, produced parkinsonism in a 23-year-old man. Unlike other drug-induced motor disturbances, the syndrome persisted for 18 months and responded to drugs that stimulate dopamine receptors. Biogenic amines and metabolites in the cerebrospinal fluid and microscopic evaluation of the brain at necropsy were consistent with damage to aminergic neurons in the substantia nigra.

Entities: Chemical Disease Species

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Year: 1979 PMID： 298352 DOI： 10.1016/0165-1781(79)90006-4

Source DB: PubMed Journal: Psychiatry Res ISSN： 0165-1781 Impact factor: 3.222

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Cited

196 in total

1. Parkinson's disorder, psychomotor problems and dopaminergic neurotoxicity in recreational ecstasy/MDMA users.

Authors: A C Parrott; T Buchanan; T M Heffernan; A Scholey; J Ling; J Rodgers
Journal: Psychopharmacology (Berl) Date: 2003-04-08 Impact factor: 4.530

2. Increased binding of 3H-L-deprenyl in spinal cords from patients with amyotrophic lateral sclerosis as demonstrated by autoradiography.

Authors: S M Aquilonius; S S Jossan; J G Ekblom; H Askmark; P G Gillberg
Journal: J Neural Transm Gen Sect Date: 1992

3. In vivo distribution of catecholamine reuptake sites in human brain gives clues to the physiopathology of MPTP-induced parkinsonism.

Authors: E Salmon; D J Brooks
Journal: J Neurol Neurosurg Psychiatry Date: 1992-02 Impact factor: 10.154

Review 4. Mimicking Parkinson's Disease in a Dish: Merits and Pitfalls of the Most Commonly used Dopaminergic In Vitro Models.

Authors: Fernanda Martins Lopes; Ivi Juliana Bristot; Leonardo Lisbôa da Motta; Richard B Parsons; Fabio Klamt
Journal: Neuromolecular Med Date: 2017-07-18 Impact factor: 3.843

5. Increased dopaminergic neuron sensitivity to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in transgenic mice expressing mutant A53T alpha-synuclein.

Authors: Wai Haung Yu; Yasuji Matsuoka; István Sziráki; Audrey Hashim; John Lafrancois; Henry Sershen; Karen E Duff
Journal: Neurochem Res Date: 2007-11-13 Impact factor: 3.996

Chronic Parkinsonism secondary to intravenous injection of meperidine analogues.

1. Parkinson's disorder, psychomotor problems and dopaminergic neurotoxicity in recreational ecstasy/MDMA users.

2. Increased binding of 3H-L-deprenyl in spinal cords from patients with amyotrophic lateral sclerosis as demonstrated by autoradiography.

3. In vivo distribution of catecholamine reuptake sites in human brain gives clues to the physiopathology of MPTP-induced parkinsonism.

Review 4. Mimicking Parkinson's Disease in a Dish: Merits and Pitfalls of the Most Commonly used Dopaminergic In Vitro Models.

5. Increased dopaminergic neuron sensitivity to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in transgenic mice expressing mutant A53T alpha-synuclein.

6. Synergistic interactions between NMDA-antagonists and L-dopa on activity in MPTP-treated mice.

7. Neurotoxic damage to the nigrostriatal system in rats following intranigral administration of MPDP+ and MPP+.

8. Increased dopamine receptor binding in duodenal mucosa of duodenal ulcer patients.

9. Does cognitive impairment in Parkinson's disease result from non-dopaminergic lesions?

Review 10. Parkinson's disease in 1984: an update.