Literature DB >> 2983420

A second nuclear protein is encoded by Epstein-Barr virus in latent infection.

K Hennessy, E Kieff.   

Abstract

A region of the Epstein-Barr virus (EBV) genome that is important in inducing cell proliferation includes a single long open reading frame. Part of this open reading frame has been fused to the lacZ gene and expressed in Escherichia coli. Antisera to the fusion protein identify a protein in the nuclei of latently infected growth-transformed lymphocytes and in Burkitt tumor cells grown in vitro. This nuclear protein is encoded by a different virus-gene than that which encodes the previously described EBV nuclear antigen, EBNA.

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Year:  1985        PMID： 2983420     DOI： 10.1126/science.2983420

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  52 in total

1.  Monoclonal and polyclonal antibodies against Epstein-Barr virus nuclear antigen 5 (EBNA-5) detect multiple protein species in Burkitt's lymphoma and lymphoblastoid cell lines.

Authors:  J Finke; M Rowe; B Kallin; I Ernberg; A Rosén; J Dillner; G Klein
Journal:  J Virol       Date:  1987-12       Impact factor: 5.103

2.  BamHI E region of the Epstein-Barr virus genome encodes three transformation-associated nuclear proteins.

Authors:  A Ricksten; B Kallin; H Alexander; J Dillner; R Fåhraeus; G Klein; R Lerner; L Rymo
Journal:  Proc Natl Acad Sci U S A       Date:  1988-02       Impact factor: 11.205

3.  Different patterns of Epstein-Barr virus gene expression and of cytotoxic T-cell recognition in B-cell lines infected with transforming (B95.8) or nontransforming (P3HR1) virus strains.

Authors:  R J Murray; L S Young; A Calender; C D Gregory; M Rowe; G M Lenoir; A B Rickinson
Journal:  J Virol       Date:  1988-03       Impact factor: 5.103

4.  An Epstein-Barr virus-producer line Akata: establishment of the cell line and analysis of viral DNA.

Authors:  K Takada; K Horinouchi; Y Ono; T Aya; T Osato; M Takahashi; S Hayasaka
Journal:  Virus Genes       Date:  1991-04       Impact factor: 2.332

5.  Expression of the Epstein-Barr virus nuclear protein 2 in rodent cells.

Authors:  T Dambaugh; F Wang; K Hennessy; E Woodland; A Rickinson; E Kieff
Journal:  J Virol       Date:  1986-08       Impact factor: 5.103

6.  EBNA-2 and EBNA-3C extensively and mutually exclusively associate with RBPJkappa in Epstein-Barr virus-transformed B lymphocytes.

Authors:  E Johannsen; C L Miller; S R Grossman; E Kieff
Journal:  J Virol       Date:  1996-06       Impact factor: 5.103

7.  Transcription of the Epstein-Barr virus genome during latency in growth-transformed lymphocytes.

Authors:  J Sample; E Kieff
Journal:  J Virol       Date:  1990-04       Impact factor: 5.103

8.  In vitro transcriptional activation, dimerization, and DNA-binding specificity of the Epstein-Barr virus Zta protein.

Authors:  P M Lieberman; A J Berk
Journal:  J Virol       Date:  1990-06       Impact factor: 5.103

9.  Spliced transcripts of human cytomegalovirus.

Authors:  W D Rawlinson; B G Barrell
Journal:  J Virol       Date:  1993-09       Impact factor: 5.103

10.  Variable expression of latent membrane protein in nasopharyngeal carcinoma can be related to methylation status of the Epstein-Barr virus BNLF-1 5'-flanking region.

Authors:  L F Hu; J Minarovits; S L Cao; B Contreras-Salazar; L Rymo; K Falk; G Klein; I Ernberg
Journal:  J Virol       Date:  1991-03       Impact factor: 5.103
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