Literature DB >> 2983310

The herpes simplex virus amplicon: analyses of cis-acting replication functions.

R R Spaete, N Frenkel.   

Abstract

Previous studies have shown that defective virus vectors (amplicons) derived from herpes simplex viruses could be efficiently propagated in virus stocks in the presence of trans-acting helper virus functions. The present study established that two separate cis-acting functions--a DNA replication origin and a cleavage/packaging signal--are required for amplicon propagation. Using deleted derivatives of cloned amplicons, we mapped one of the viral DNA replication origins (ori-2 or oriL) at coordinate 0.422 of the standard HSV-1 genome and at an equivalent position within the HSV-2 genome.

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Year:  1985        PMID: 2983310      PMCID: PMC397112          DOI: 10.1073/pnas.82.3.694

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  12 in total

Review 1.  The structure and isomerization of herpes simplex virus genomes.

Authors:  B Roizman
Journal:  Cell       Date:  1979-03       Impact factor: 41.582

2.  Electron microscopy of herpes simplex virus DNA molecules isolated from infected cells by centrifugation in CsCl density gradients.

Authors:  A Friedmann; J Shlomai; Y Becker
Journal:  J Gen Virol       Date:  1977-03       Impact factor: 3.891

3.  Site-specific inversion sequence of the herpes simplex virus genome: domain and structural features.

Authors:  E S Mocarski; B Roizman
Journal:  Proc Natl Acad Sci U S A       Date:  1981-11       Impact factor: 11.205

4.  The herpes simplex virus amplicon: a new eucaryotic defective-virus cloning-amplifying vector.

Authors:  R R Spaete; N Frenkel
Journal:  Cell       Date:  1982-08       Impact factor: 41.582

5.  Herpesvirus-dependent amplification and inversion of cell-associated viral thymidine kinase gene flanked by viral a sequences and linked to an origin of viral DNA replication.

Authors:  E S Mocarski; B Roizman
Journal:  Proc Natl Acad Sci U S A       Date:  1982-09       Impact factor: 11.205

6.  Site-specific cleavage/packaging of herpes simplex virus DNA and the selective maturation of nucleocapsids containing full-length viral DNA.

Authors:  D A Vlazny; A Kwong; N Frenkel
Journal:  Proc Natl Acad Sci U S A       Date:  1982-03       Impact factor: 11.205

7.  Class I defective herpes simplex virus DNA as a molecular cloning vehicle in eucaryotic cells.

Authors:  J W Barnett; D A Eppstein; H W Chan
Journal:  J Virol       Date:  1983-11       Impact factor: 5.103

8.  Characterization of the TRS/IRS origin of DNA replication of herpes simplex virus type 1.

Authors:  N D Stow; E C McMonagle
Journal:  Virology       Date:  1983-10-30       Impact factor: 3.616

9.  Replication of herpes simplex virus DNA: localization of replication recognition signals within defective virus genomes.

Authors:  D A Vlazny; N Frenkel
Journal:  Proc Natl Acad Sci U S A       Date:  1981-02       Impact factor: 11.205

10.  Localization of an origin of DNA replication within the TRS/IRS repeated region of the herpes simplex virus type 1 genome.

Authors:  N D Stow
Journal:  EMBO J       Date:  1982       Impact factor: 11.598

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  51 in total

Review 1.  Virus-based gene delivery systems.

Authors:  Cathryn Mah; Barry J Byrne; Terence R Flotte
Journal:  Clin Pharmacokinet       Date:  2002       Impact factor: 6.447

2.  Characterization of a herpes simplex virus sequence which binds a cellular protein as either a single-stranded or double-stranded DNA or RNA.

Authors:  L McCormick; R J Roller; B Roizman
Journal:  J Virol       Date:  1992-06       Impact factor: 5.103

3.  Use of Adeno-Associated and Herpes Simplex Viral Vectors for In Vivo Neuronal Expression in Mice.

Authors:  Rachel D Penrod; Audrey M Wells; William A Carlezon; Christopher W Cowan
Journal:  Curr Protoc Neurosci       Date:  2015-10-01

4.  Herpes simplex virus type 1 oriL is not required for virus replication or for the establishment and reactivation of latent infection in mice.

Authors:  M Polvino-Bodnar; P K Orberg; P A Schaffer
Journal:  J Virol       Date:  1987-11       Impact factor: 5.103

5.  Efficient site-specific integration of large transgenes by an enhanced herpes simplex virus/adeno-associated virus hybrid amplicon vector.

Authors:  Qiang Liu; Claudio F Perez; Yaming Wang
Journal:  J Virol       Date:  2006-02       Impact factor: 5.103

6.  Mutations in a herpes simplex virus type 1 origin that inhibit interaction with origin-binding protein also inhibit DNA replication.

Authors:  T R Hernandez; R E Dutch; I R Lehman; C Gustafsson; P Elias
Journal:  J Virol       Date:  1991-03       Impact factor: 5.103

7.  An enhanced packaging system for helper-dependent herpes simplex virus vectors.

Authors:  T A Stavropoulos; C A Strathdee
Journal:  J Virol       Date:  1998-09       Impact factor: 5.103

Review 8.  Targeting the central nervous system with herpes simplex virus / Sleeping Beauty hybrid amplicon vectors.

Authors:  Suresh de Silva; William J Bowers
Journal:  Curr Gene Ther       Date:  2011-10       Impact factor: 4.391

9.  A host cell protein binds to a highly conserved sequence element (pac-2) within the cytomegalovirus a sequence.

Authors:  G W Kemble; E S Mocarski
Journal:  J Virol       Date:  1989-11       Impact factor: 5.103

10.  The UL6 gene product forms the portal for entry of DNA into the herpes simplex virus capsid.

Authors:  W W Newcomb; R M Juhas; D R Thomsen; F L Homa; A D Burch; S K Weller; J C Brown
Journal:  J Virol       Date:  2001-11       Impact factor: 5.103

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