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Literature DB >> 2982918

Human B lymphoma cell line producing B cell growth factor.

Abstract

Namalva, a human B cell lymphoma line, produced a factor with a molecular weight of approximately 60,000 which enhanced the proliferation of normal activated human B lymphocytes. The factor also enhanced the proliferation of certain B cell lines. It can be distinguished physiologically and biochemically from other lymphokines known to enhance B cell proliferation, namely, interleukin (IL) 1, IL 2, and interferon. The production of B cell growth factor by B cell tumor lines may contribute to their ability to grow autonomously and may reflect an important component of the neoplastic potential of the cell. B cell growth factor produced by tumors may also affect normal cells in vivo.

Entities: Chemical Disease Gene Species

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Year: 1985 PMID： 2982918 PMCID： PMC423567 DOI： 10.1172/JCI111754

Source DB: PubMed Journal: J Clin Invest ISSN： 0021-9738 Impact factor: 14.808

32 in total

1. Proteins of Epstein-Barr virus. I. Analysis of the polypeptides of purified enveloped Epstein-Barr virus.

Authors: M Dolyniuk; R Pritchett; E Kieff
Journal: J Virol Date: 1976-03 Impact factor: 5.103

2. Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors: U K Laemmli
Journal: Nature Date: 1970-08-15 Impact factor: 49.962

3. Spontaneous production of human interferon.

Authors: L A Pickering; L H Kronenberg; W E Stewart
Journal: Proc Natl Acad Sci U S A Date: 1980-10 Impact factor: 11.205

4. Preparation of lymphocyte-activating factor from continuous murine macrophage cell lines.

Authors: L B Lachman; M P Hacker; G T Blyden; R E Handschumacher
Journal: Cell Immunol Date: 1977-12 Impact factor: 4.868

5. Radioiodination by use of the Bolton-Hunter and related reagents.

Authors: J J Langone
Journal: Methods Enzymol Date: 1980 Impact factor: 1.600

6. T cell-dependent activation of resting B cells: requirement for both nonspecific unrestricted and antigen-specific Ia-restricted soluble factors.

Authors: J Anderson; F Melchers
Journal: Proc Natl Acad Sci U S A Date: 1981-04 Impact factor: 11.205

7. Immortalized B lymphocytes produce B-cell growth factor.

Authors: J Gordon; S C Ley; M D Melamed; L S English; N C Hughes-Jones
Journal: Nature Date: 1984 Jul 12-18 Impact factor: 49.962

8. Immune interferon in the circulation of patients with autoimmune disease.

Authors: J J Hooks; H M Moutsopoulos; S A Geis; N I Stahl; J L Decker; A L Notkins
Journal: N Engl J Med Date: 1979-07-05 Impact factor: 91.245

9. Bidirectional amplification of macrophage-lymphocyte interactions: enhanced lymphocyte activation factor production by activated adherent mouse peritoneal cells.

Authors: M S Meltzer; J J Oppenheim
Journal: J Immunol Date: 1977-01 Impact factor: 5.422

10. Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition.

Authors: J W Kappler; B Skidmore; J White; P Marrack
Journal: J Exp Med Date: 1981-05-01 Impact factor: 14.307

22 in total

1. Presence of preactivated T cells in hemodialyzed patients: their possible role in altered immunity.

Authors: L Chatenoud; B Dugas; G Beaurain; M Touam; T Drueke; A Vasquez; P Galanaud; J F Bach; J F Delfraissy
Journal: Proc Natl Acad Sci U S A Date: 1986-10 Impact factor: 11.205

2. Response of neoplasms of B cell lineage to the proliferative effects of B cell growth factor and the phorbol ester TPA.

Authors: M C Kinney; R D Collins; J Whitlock; J B Cousar; L B Vogler
Journal: Am J Pathol Date: 1989-04 Impact factor: 4.307

Human B lymphoma cell line producing B cell growth factor.

1. Proteins of Epstein-Barr virus. I. Analysis of the polypeptides of purified enveloped Epstein-Barr virus.

2. Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

3. Spontaneous production of human interferon.

4. Preparation of lymphocyte-activating factor from continuous murine macrophage cell lines.

5. Radioiodination by use of the Bolton-Hunter and related reagents.

6. T cell-dependent activation of resting B cells: requirement for both nonspecific unrestricted and antigen-specific Ia-restricted soluble factors.

7. Immortalized B lymphocytes produce B-cell growth factor.

8. Immune interferon in the circulation of patients with autoimmune disease.

9. Bidirectional amplification of macrophage-lymphocyte interactions: enhanced lymphocyte activation factor production by activated adherent mouse peritoneal cells.

10. Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition.

1. Presence of preactivated T cells in hemodialyzed patients: their possible role in altered immunity.

2. Response of neoplasms of B cell lineage to the proliferative effects of B cell growth factor and the phorbol ester TPA.

3. Activation of human B cells mediated through two distinct cell surface differentiation antigens, Bp35 and Bp50.

4. Modulation of the response to B-cell growth factor (BCGF) of hairy cells from a patient under IFN-alpha therapy.

5. Lymphoma cell culture under serum-free conditions.

6. Identification of a cDNA for a human high-molecular-weight B-cell growth factor.

Review 7. Advances in understanding the pathogenesis of primary Sjögren's syndrome.

8. CD40 expression in Hodgkin's disease.

9. Control of human B cell tumor growth in severe combined immunodeficiency mice by monoclonal anti-B cell antibodies.

10. Spontaneous production of B cell growth factors by SLE lymphocytes.