| Literature DB >> 2982899 |
J L Belsky, B Cuello, L W Swanson, D M Simmons, R M Jarrett, F Braza.
Abstract
A patient with Cushing's syndrome is described who had a metastatic medullary carcinoma of the thyroid which contained corticotropin-releasing factor. ACTH was found by an immunohistochemical method in the patient's pituitary, but not in the thyroid tumor. This is the second report demonstrating corticotropin-releasing factor in tumor tissue in this syndrome. Wider use of immunohistological methods can help distinguish this variety from other tumors associated with the ectopic ACTH syndrome when bioassays are not available.Entities:
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Year: 1985 PMID: 2982899 DOI: 10.1210/jcem-60-3-496
Source DB: PubMed Journal: J Clin Endocrinol Metab ISSN: 0021-972X Impact factor: 5.958