Literature DB >> 2982689

Methylation pattern of the bovine leukemia provirus genome in bovine leukemic cells.

Y Ogawa, N Sagata, J Tsuzuku-Kawamura, M Onuma, H Izawa, Y Ikawa.   

Abstract

All the known genes of the bovine leukemia proviral genome were found to be heavily methylated in both fresh and short-term-cultured leukemic cells, the latter of which expressed viral antigens. However, the pXBL region appeared to be mostly demethylated or at least hypomethylated in both cells, indicating that there is a non-uniform methylation pattern of the proviral genome.

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Year:  1985        PMID: 2982689

Source DB:  PubMed          Journal:  Jpn J Cancer Res        ISSN: 0910-5050


  3 in total

1.  5'-long terminal repeat-selective CpG methylation of latent human T-cell leukemia virus type 1 provirus in vitro and in vivo.

Authors:  Tsukasa Koiwa; Akiko Hamano-Usami; Takaomi Ishida; Akihiko Okayama; Kazunari Yamaguchi; Shimeru Kamihira; Toshiki Watanabe
Journal:  J Virol       Date:  2002-09       Impact factor: 5.103

2.  Latency of viral expression in vivo is not related to CpG methylation in the U3 region and part of the R region of the long terminal repeat of bovine leukemia virus.

Authors:  Shigeru Tajima; Masako Tsukamoto; Yoko Aida
Journal:  J Virol       Date:  2003-04       Impact factor: 5.103

3.  The screening of cattle with potential for developing leukemia by using monoclonal antibody against bovine leukemia cells.

Authors:  M Onuma; Y Yasutomi; H M Okada; K Matsukawa; H Yoshikawa; T Yoshikawa; K Okada; K Takahashi; R Kirisawa; Y Kawakami
Journal:  Jpn J Cancer Res       Date:  1988-02
  3 in total

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